slot game rules Harden urges NBA fans to ‘cherish' Steph vs. LeBron battlesPowerful weight-loss drugs are expanding use of U.S. health care as patients starting prescriptions are diagnosed with obesity-related conditions or take the drugs to become eligible for other services, health records and discussions with doctors show. An exclusive analysis of hundreds of thousands of electronic patient records by health data firm Truveta found slight, but measurable, increases in first-time diagnoses of sleep apnea, cardiovascular disease, and type 2 diabetes within 15 days of an initial prescription for a GLP-1 weight-loss drug between 2020 and 2024. In addition to obesity-related conditions, some patients are being prescribed the drugs to lose weight and become eligible for services, including organ transplants, fertility treatments or knee replacements, according to interviews with seven doctors and five other health experts. "This is a population that previously felt stigmatized by health care providers and often didn't return. But now that they're actually seeing themselves get healthier, asking clinicians questions and engaging more, I do think we're seeing new patients," said Dr. Rekha Kumar, a New York endocrinologist and obesity medicine specialist. Novo Nordisk's Wegovy and Ozempic and Eli Lilly's Zepbound and Mounjaro have been shown to lead to average weight loss of at least 15%. Andrew Friedson, director of health economics at the Milken Institute and three other experts said the impact of the drugs on overall healthcare use is not yet clear. The new diagnoses could mean higher initial spending, but early detection could save costs down the line, he said. Dr. Courtney Younglove, an obesity medicine specialist and founder of Heartland Weight Loss clinic in Overland Park, Kansas, said she has referred obesity patients for long-delayed pap smears and other routine care, including colonoscopies. Many overweight patients avoid doctors and routine tests for years due to the stigma and bias they often encounter, she said. “A lot of people with obesity don't do a lot of preventive health maintenance." Phil, a 43-year-old Chicago technology executive who asked for his full name to be withheld for privacy reasons, generally avoided doctors before receiving a GLP-1 prescription from a telehealth provider in early 2023. He said he told his regular physician about the medication months later, after he had lost more than 30 lbs, and was taken aback by her supportive response. He decided then to advocate more for himself and ask for help with other conditions, including addiction and mental health. "It gave me the courage to ask," he said. The Truveta analysis found that for every 1,000 patients with a first-time GLP-1 prescription, 42 were diagnosed with type 2 diabetes within 15 days in 2024, up from 32 in 2020. Over the same period, the number of sleep apnea diagnoses per 1,000 patients rose to 11 from 8 and the number of cardiovascular disease diagnoses increased to 15 from 13. The most obese patients were twice as likely as people who were less overweight to receive a type 2 diabetes diagnosis, and three times as likely to be diagnosed with sleep apnea, the Truveta data showed. The analysis was based on 33,630 first-time GLP-1 prescriptions for overweight or obese patients in 2020 and 224,496 in the first 10 months of 2024. Lilly declined to directly comment on the data, saying in an emailed statement "it is important that adults living with obesity receive appropriate diagnosis and access to evidence-based care." Novo Nordisk also declined to comment directly, noting its aim "to address unmet needs for a wider range of patients." QUALIFYING FOR SURGERIES ResMed, which sells sleep apnea devices, had revenue growth of 11% for its fiscal year ending in June - a trend the company attributed in part to the GLP-1 drugs. The medications are "bringing people into primary care like never before," ResMed CEO Michael Farrell said at the company's recent shareholder meeting. In addition to things like sleep apnea, the weight-loss drugs could lead to more joint replacements, said Sara Mallatt, director of healthcare research at market analysis firm AlphaSense. "As people's BMIs come down, they'll be eligible for surgeries they wouldn't otherwise," she said. "No one is saying this is happening in a meaningful way right now, but we think it will." University of Chicago Medicine last year launched a weight-loss clinic aimed at helping prospective organ transplant patients lose weight to qualify for surgery, with the GLP-1 drugs playing a key role. "Before they had a place to send these patients, which is our clinic, the scheduler would just say, 'hey, what's your weight, what's your height, what's your BMI,' and if they didn't fit their criteria, they would just tell them to lose weight on their own," said Anesia Reticker, the center's clinical pharmacist specialist. Retired Indiana steelworker Bensabio Guajardo, 68, was prescribed Ozempic at the clinic in 2023 when he was deemed too obese for a double lung transplant needed to keep him alive after pulmonary fibrosis made breathing increasingly difficult. "It helped me a lot. It took my cravings away," Guajardo said. After losing around 90 pounds and stopping the drug ahead of a successful surgery in May, his doctor put him back on it to control high blood sugar. Reticker said the program has received about 100 referrals over the past year from transplant centers in the Chicago area.A California-based laboratory is set to lay the groundwork for the next evolution of extreme ultraviolet (EUV) lithography. Led by Lawrence Livermore National Laboratory (LLNL), the project aims for the next evolution of EUV lithography, centered around the lab-developed driver system named the Big Aperture Thulium (BAT) laser. The LLNL-led project will test the BAT laser’s ability to increase EUV source efficiency by about 10 times when compared to carbon dioxide (CO2) lasers, the current industry standard, according to the lab. LLNL maintains that this could lead to a next-generation “beyond EUV” (BEUV) lithography system producing chips that are smaller, more powerful, and faster to manufacture while using less electricity. Lab performed proof of concept laser demonstrations LLNL laser physicist Brendan Reagan stated that the lab has performed theoretical plasma simulations and proof of concept laser demonstrations over the past five years, which lay the foundations for this project. “Our work has already had quite an impact in the EUV lithography community, so now we’re excited to take this next step,” added Reagan. The lab claims that EUV lithography involves high-power lasers firing at tens of thousands of droplets of tin per second. The laser heats the droplets, each measuring about 30 millionths of a meter, to half a million degrees centigrade to produce a plasma that generates ultraviolet light with a wavelength of 13.5 nanometers. Energy efficiency of existing EUV lithography sources Special multi-layer mirrors guide the light through plates called masks, which hold the intricate patterns of the integrated circuits for semiconductor wafers. The light projects the pattern onto a photoresist layer that is etched away to leave the integrated circuits on the chip, according to a press release by LLNL. The project also aims to investigate the primary hypothesis that the energy efficiency of existing EUV lithography sources for semiconductor production can be improved with technology developed for the novel petawatt-class BAT laser, which uses thulium-doped yttrium lithium fluoride (Tm:YLF) as the gain medium through which the power and intensity of laser beams are increased, as per the release. Scientists have planned to conduct a demonstration pairing the compact high-rep-rate BAT laser with technologies that generate sources of EUV light using shaped nanosecond pulses and high-energy x-rays and particles using ultrashort sub-picosecond pulses. Semiconductor industry to get benefit Williams highlighted that this project will establish the first high-power, high-repetition-rate, about 2-micron laser at LLNL. This advancement is expected to benefit the semiconductor industry. Williams emphasized that the BAT laser’s capabilities will have implications beyond EUV generation, significantly impacting high-energy density (HED) physics and inertial fusion energy. LLNL also maintained that the semiconductor industry has been engaged in a constant race to make each generation of microprocessors smaller yet more powerful by packing as many integrated circuits and other features as possible into one chip. For the past several years, EUV lithography has taken the forefront because it uses EUV light to etch microscopic circuits as small as a few nanometers onto advanced chips and processors. LLNL has long pioneered the development of EUV lithography, including early spectroscopic studies that formed the foundation of plasma-based EUV sources.

I.F. Fire Department seeks donations for annual toy and supply drive

Hurricanes visit the Panthers in Eastern Conference actionNorthern Kentucky knocks off South Carolina State 58-47

Japan, Sweden agree to upgrade ties to strategic partnership

Sony to Take On Nintendo with New PlayStation Handheld - IGN Daily FixRumble Announces Bitcoin Treasury Strategy

Washington Commanders release 2023 first-round pick Emmanuel ForbesTyron Smith Headed to IR, Xavier Newman Activated

Summers scores 22 off the bench, Indiana State downs St. Louis Pharmacy 101-53China, Pakistan share latest non-wood forestry findingsReed scores 15 off the bench, Tulsa downs Mississippi Valley State 93-48The Boston Bruins hope to continue their winning start to Joe Sacco's tenure as interim coach as they begin a stretch of three games in four nights around Thanksgiving on Tuesday against the Vancouver Canucks. Sacco has emphasized shoring things up defensively and his team has delivered, allowing a combined 42 shots on goal across only their second set of back-to-back regulation wins all season on Thursday against Utah (1-0 score) and Saturday in Detroit (2-1). Javascript is required for you to be able to read premium content. Please enable it in your browser settings. Stacker analyzed data from the Centers for Disease Control and Prevention to identify the most common settings for foodborne outbreaks in Georgia. Click for more. Most common settings for foodborne outbreaks in Georgia

NEW YORK (AP) — U.S. stocks rose Monday, with those benefiting the most from lower interest rates and a stronger economy leading the way. The S&P 500 climbed 0.3% to pull closer to its all-time high set two weeks ago. The Dow Jones Industrial Average added 440 points, or 1%, to its own record set on Friday, while the Nasdaq composite rose 0.3%. Treasury yields also eased in the bond market amid what some analysts called a “Bessent bounce” after President-elect Donald Trump said he wants Scott Bessent , a hedge fund manager, to be his Treasury Secretary. Bessent has argued for reducing the U.S. government’s deficit, which is how much more it spends than it takes in through taxes and other revenue. Such an approach could soothe worries on Wall Street that Trump’s policies may lead to a much bigger deficit, which in turn would put upward pressure on Treasury yields. After climbing above 4.44% immediately after Trump’s election, the yield on the 10-year Treasury fell back to 4.26% Monday, down from 4.41% late Friday. That’s a notable move, and lower yields make it cheaper for all kinds of companies and households to borrow money. They also give a boost to prices for stocks and other investments. That helped stocks of smaller companies lead the way, and the Russell 2000 index of smaller stocks jumped 1.5%. It finished just shy of its all-time high, which was set three years ago. Smaller companies can feel bigger boosts from lower borrowing costs because of the need for many to borrow to grow. The two-year Treasury yield, which more closely tracks the market’s expectations for what the Federal Reserve will do with overnight interest rates, also eased sharply. The Fed began cutting its main interest rate just a couple months ago from a two-decade high, hoping to keep the job market humming after bringing inflation nearly all the way down to its 2% target. But immediately after Trump’s victory, traders had reduced bets for how many cuts the Fed may deliver next year. They were worried Trump’s preference for lower tax rates and higher spending on the border would balloon the national debt. A report coming on Wednesday could influence how much the Fed may cut rates. Economists expect it to show that an underlying inflation trend the Fed prefers to use accelerated to 2.8% last month from 2.7% in September. Higher inflation would make the Fed more reluctant to cut rates as deeply or as quickly as it would otherwise. Goldman Sachs economist David Mericle expects that to slow by the end of next year to 2.4%, but he said inflation would be even lower if not for expected tariff increases on imports from China and autos favored by Trump. In the stock market, Bath & Body Works jumped 16.5% after delivering stronger profit for the latest quarter than analysts expected. The seller of personal care products and home fragrances also raised its financial forecasts for the full year, even though it still sees a “volatile retail environment” and a shorter holiday shopping season this year. Much focus has been on how resilient U.S. shoppers can remain, given high prices across the economy and still-high interest rates. Last week, two major retailers sent mixed messages. Target tumbled after giving a dour forecast for the holiday shopping season. It followed Walmart , which gave a much more encouraging outlook. Another big retailer, Macy’s, said Monday its sales for the latest quarter were in line with its expectations, but it will delay the release of its full financial results. It found a single employee had intentionally hid up to $154 million in delivery expenses, and it needs more time to complete its investigation. Macy’s stock fell 2.2%. Among the market’s leaders were several companies related to the housing industry. Monday’s drop in Treasury yields could translate into easier mortgage rates, which could spur activity for housing. Builders FirstSource, a supplier or building materials, rose 5.9%. Homebuilders, D.R. Horton, PulteGroup and Lennar all rose at least 5.6%. All told, the S&P 500 rose 18.03 points to 5,987.37. The Dow Jones Industrial Average jumped 440.06 to 44,736.57, and the Nasdaq composite gained 51.18 to 19,054.84. In stock markets abroad, indexes moved modestly across much of Europe after finishing mixed in Asia. In the crypto market, bitcoin was trading below $95,000 after threatening to hit $100,000 late last week for the first time. AP Business Writer Elaine Kurtenbach contributed.During the third quarter of the 89th edition of the Iron Bowl , Auburn called a bubble screen to the left side of the formation. Tigers quarterback Payton Thorne threw it out to the left, but the pass was dropped. That was just the beginning of the action. Alabama safety Malachi Moore, who was being blocked on the play by an Auburn wide receiver, tussled with the receiver into the Tigers' sideline. Multiple Auburn players ran over, and a scuffle occurred. Malachi Moore and DeVonta Smith both called for unsportsmanlike conduct penalties pic.twitter.com/NlZKplvpy8 A plethora of Alabama players ran to the defense of their safety with Devonta Smith, Zabien Brown, and Jihaad Campbell all involved. Smith and Moore were assessed unsportsmanlike penalty calls from the incident. This wasn't the only scuffle of the college football Saturday as Michigan and Ohio State battled each other post game after the Wolverine attempted to plant their flag on the the Buckeyes logo. Rivalries are one of the best aspects of college football with some of the most notorious moments coming on rivalry weekend, but fights are one of the most dangerous aspects of rivalry games. Luckily, nothing serious seemed to breakout and no one emerged with an injury from the Alabama versus Auburn event that took place during the third quarter. Alabama is fighting for its playoff lives in the Iron Bowl as a win would move them to 9-3 and give them a shot to make the 12-team field. Auburn is hoping to just make a bowl game as they entered Saturday's contest at just 5-6. Related: Nick Saban Didn't Hesitate When Making His Iron Bowl Pick

Vancouver Canucks (12-7-3, in the Pacific Division) vs. Detroit Red Wings (10-11-2, in the Atlantic Division) Detroit; Sunday, 12:30 p.m. EST BOTTOM LINE: The Vancouver Canucks visit the Detroit Red Wings after the Canucks took down the Buffalo Sabres 4-3 in overtime. Detroit has gone 5-6-1 at home and 10-11-2 overall. The Red Wings have gone 3-3-2 in games they serve more penalty minutes than their opponents. Vancouver has a 12-7-3 record overall and a 9-2-0 record on the road. The Canucks have a +two scoring differential, with 71 total goals scored and 69 given up. Sunday's game is the first time these teams square off this season. TOP PERFORMERS: Dylan Larkin has 12 goals and six assists for the Red Wings. Lucas Raymond has six goals and four assists over the past 10 games. Quinn Hughes has five goals and 20 assists for the Canucks. Elias Pettersson has scored five goals with eight assists over the last 10 games. LAST 10 GAMES: Red Wings: 4-5-1, averaging 2.5 goals, 4.3 assists, 2.9 penalties and 6.3 penalty minutes while giving up 2.9 goals per game. Canucks: 5-5-0, averaging 3.2 goals, 5.7 assists, 3.7 penalties and 9.1 penalty minutes while giving up 3.2 goals per game. INJURIES: Red Wings: None listed. Canucks: None listed. The Associated Press created this story using technology provided by Data Skrive and data from Sportradar .Copy link Copied Copy link Copied Subscribe to gift this article Gift 5 articles to anyone you choose each month when you subscribe. Already a subscriber? Login The inauguration of Donald Trump as president of the US will take place on January 20 — the same day as the opening of the World Economic Forum in Davos. Since the end of the Cold War, the annual Davos meeting — which brings together business and political leaders from all over the world — has become a symbol of elite-driven globalisation. Financial Times Copy link Copied Copy link Copied Subscribe to gift this article Gift 5 articles to anyone you choose each month when you subscribe. Already a subscriber? Login Follow the topics, people and companies that matter to you. Fetching latest articles

MOREHEAD, Ky. (AP) — Isaiah Smith ran for a career-high 205 yards on 31 carries and scored a touchdown and San Diego beat Morehead State 37-14 in a season-ending contest for both teams on Saturday. Grant Sergent threw for 184 yards and two touchdowns for San Diego (8-3, 6-2 Pioneer Football League) which ended the season with a four-game win streak and winners of six of seven. The Toreros finished in sole possession of second place in the PFL behind Drake (7-1), which clinched the league outright with a 49-10 win over Stetson on Saturday. Drake beat San Diego 30-28 on a walk-off field goal on Sept. 28 in Des Moines, Iowa. Bryce Patterson threw for 133 yards and a touchdown and James Louis ran for a touchdown for the Eagles (7-5, 5-3). ___ Get poll alerts and updates on the AP Top 25 throughout the season. Sign up here . AP collegebasketball: https://apnews.com/hub/ap-top-25-college-basketball-poll and https://apnews.com/hub/college-basketballOur community members are treated to special offers, promotions and adverts from us and our partners. You can check out at any time. More info A year ago, I made the decision to cut out ultra-processed food and refined sugar from my diet. Like many of us, I kick off each new year with a host of health resolutions, usually feeling sluggish and bloated after the festive indulgence of December. But by February, these ambitions typically fall by the wayside. However, 2024 was a game-changer for me, and I believe the changes I implemented a year ago will stick with me for life. They're sustainable, enjoyable, and have taught me a lot about food and those who produce it. Far from feeling deprived or restricted, I've actually expanded my culinary horizons and found the whole process rewarding and enlightening. As a result, I've noticed several significant changes in my life. But before I delve into those, let's briefly discuss what ultra-processed foods are and how I eliminated them from my diet. It's essential to acknowledge that no judgement should be cast on individuals' dietary choices. The way we purchase food, the hustle of our daily routines, and tight budgets all play significant roles in shaping our eating habits – and naturally, we enjoy indulging in our favourite foods, reports Surrey Live. However, more insidious are the tactics employed by major global food producers to increase our consumption. These strategies include savvy marketing, questionable health claims on packaging, and the creation of hyper-palatable products that leave us craving more. Among the most prevalent ultra-processed foods (UPFs) are packaged bread, breakfast cereals and granola, flavoured yoghurt, chocolate, biscuits, crisps, energy and granola bars, fizzy drinks, and ready meals. Up until this year, my own breakfast consisted of granola every day, under the impression it was a healthy choice. Accompanied by fruit and flavoured yoghurt, I believed I was kickstarting my day...

Gaetz withdraws nameMohamed Salah said he is still "far away" from resolving his future at Liverpool after scoring once and creating two more goals in a 5-0 win at West Ham that moved Arne Slot's team eight points clear at the top of the Premier League . Salah, 32, can open negotiations with non-English clubs from this Wednesday (Jan 1) about a free agent transfer at the end of the season with his existing contract due to expire on June 30. Liverpool teammates Virgil van Dijk and Trent Alexander-Arnold also enter the final six months of their Anfield contracts this week. But despite the ongoing uncertainty surrounding his contract beyond next summer, Salah said his focus is on winning the title with Liverpool and that he is no closer to agreeing a new deal. "No we are far away from that [contract] and I don't want to put anything in the media," Salah told Sky Sports. "The only thing on my mind is I want Liverpool to win the league and I want to be part of that. "I will do my best for the team to win the trophy. There is a few other teams catching up with us and we need to stay focused and humble and go again. "I am just trying to enjoy the game. At the end of the day I came here for the result and I wanted to do something in the game, but I am almost hungry for more." Liverpool manager Arne Slot said he is unconcerned about the three senior players being able to talk to overseas clubs from Jan 1, saying that he believes he still has come control over their destiny. "I think I have a lot of control over what they do," Slot said. "If they're on a training pitch, if they're in a meeting with me, but talking about the private lives, I don't have control about them. "So that was the situation I have a year ago. There's been a situation as long as I'm a manager, but I have control to a certain extent over them from what I expect from them on the pitch and I'm really pleased to see what Virgil brings, what Trent brings and what Mo brings. "Now the positive thing for me is that for four or five months it was only Trent Mo and Virgil, what you guys were talking about. "And I assume, and don't let me down please, that people now are going to talk about how many players we are going to bring in the upcoming month and which other player is going to leave. So I get some other questions as well. Not only about these!" When asked if Liverpool had any plans for January, however, Slot said he is happy with the squad at his disposal. "I said this six months ago and everybody goes, "Is this guy crazy?" Slot said. "But I think the players showed that the confidence the club and me as well had in them was well deserved." Slot, meanwhile, described Salah as extraordinary after the 32-year-old registered his 17th leaguer goal and 13th assist in the win at West Ham. "The word extraordinary is something I've heard a lot in the last six months and he truly deserves this and probably in the last eight years too," Slot said. "But I'm involved in the last half years, so yeah, I don't think he keeps surprising us. "We know what a player he is and we know he's able to do so, but apart from that, he works really hard for the team also when the other team has the ball and yeah, we can only hope that he can keep bringing these performances in. "But I would like to add that if he scores, there's also a lead up to him scoring. So there are also other players that bring him in these positions, but if you bring Mo in these positions, he's extraordinary. Definitely."

Online child exploitation spiked during lockdowns. Police worry it's here to stayBROC Community Action in Rutland has been stocking up on 400 turkeys this year, with the goal to help as many families as possible to have a proper Thanksgiving meal.