Arnold and Salah have been integral to Liverpool's recent success, with the former being a stalwart in defense and the latter a prolific goal scorer. However, rumors have been circulating in the football world suggesting that both players could be on the move in the near future. Arnold has attracted interest from several top European clubs, while Salah's contract situation has raised doubts about his long-term future at Anfield.
XDefiant Shuts Down In June 2025, Ubisoft Closes Two OfficesFianna Fail and Fine Gael eye independent TDs as option to secure Dail majority
Walking through the familiar halls of the school, Zhang Guimei's heart swelled with nostalgia. She remembered the days when she was just a young student, full of dreams and aspirations. And now, as a newly minted police officer, she felt a sense of pride and accomplishment that was overwhelming.
Jimmy Carter, the 39th U.S. president, has died at 100Houston's Al-Shaair apologizes for hit on Jacksonville's Lawrence that led to concussion HOUSTON (AP) — Houston’s Azeez Al-Shaair took to X to apologize to Jacksonville’s Trevor Lawrence after his violent blow to the quarterback’s facemask led to him being carted off the field with a concussion. Back in the starting lineup after missing two games with a sprained left shoulder, Lawrence scrambled left on a second-and-7 play in the second quarter of Houston’s 23-20 win on Sunday. He initiated a slide before Al-Shaair raised his forearm and unleashed on the defenseless quarterback. In the long post, Al-Shaair says "To Trevor I genuinely apologize to you for what ended up happening.” Jets are sticking with struggling Aaron Rodgers as their starting quarterback Aaron Rodgers will remain the New York Jets’ starting quarterback despite speculation the team could bench him in what has been a disappointing season. Interim coach Jeff Ulbrich said during a video call that he still believes Rodgers, who turned 41 on Monday, gives the Jets their best chance to win. Rodgers was 21 of 39 for 185 yards and touchdown passes to Davante Adams and Isaiah Davis but also had an interception returned 92 yards for a touchdown by Leonard Williams in the Jets’ 26-21 loss to Seattle on Sunday. Hall of Famer Randy Moss reveals he's 'battling something' internal and asks for prayers Hall of Fame wide receiver Randy Moss revealed he’s dealing with a health issue and asked fans to pray for him and his family. The 47-year-old ESPN football analyst made the announcement on Instagram from the set of the network’s “Sunday NFL Countdown” show. He directed his message to men and urged them to get checkups and bloodwork done, without specifying for any particular illness. Moss explained why he’s been wearing tinted sunglasses, saying, “I’m battling something, man, and it’s something internal, your boy is going to get through it.” College playoff bracket offers last dress rehearsal and one more chance to see where the SEC stands The next set of College Football Playoff rankings will be released Tuesday night under heavy scrutiny before the final bracket is set on Sunday. It will be one last chance to see just how much the selection committee loves the Southeastern Conference. The best gauge will be whether Miami, which suffered its second loss over the weekend, is placed behind any or all three SEC teams with three losses — Alabama, Mississippi and South Carolina, all of which are coming off wins. Whatever happens, the SEC is likely to have at least five teams in the 12-team field when the final bracket comes out. Mollie Marcoux Samaan stepping down as LPGA commissioner after 3 1/2 years of record prize money Mollie Marcoux Samaan is leaving after more than three years as LPGA commissioner. In a surprise announcement Monday, Marcoux Samaan says she will step down in January, just three weeks before the LPGA starts its 75th season. Liz Moore is the chief legal and technology officer. She'll be serving as interim commissioner until a search committee can find a permanent replacement. Marcoux Samaan was the athletic director at Princeton when she took over the LPGA in May 2021. Prize money has soared during her tenure. She also has faced criticism for the LPGA not gaining in popularity during a rise in women's sports. Kansas holds off Auburn for No. 1 in AP Top 25 as SEC grabs 3 of top 4 spots; UConn slides to No. 25 Kansas continues to hold the No. 1 ranking in The Associated Press Top 25 men’s college basketball poll. Auburn is pushing the Jayhawks in the latest poll after winning the Maui Invitational and checked in at No. 2. Two-time reigning national champion UConn nearly fell out entirely after an 0-3 week at Maui, falling from No. 2 to 25th. The Southeastern Conference had three of the top four teams with No. 3 Tennessee and No. 4 Kentucky behind the Tigers. The poll featured six new teams, headlined by No. 13 Oregon, No. 16 Memphis and No. 18 Pittsburgh. TCU, Duke climb into top 10, Notre Dame drops in women's AP Top 25; UCLA and UConn remain 1-2 TCU has its best ranking ever in The Associated Press Top 25 women’s basketball poll after a convincing win over Notre Dame. The Horned Frogs jumped eight spots to No. 9, the first time the school has ever been in the top 10. The Fighting Irish, who were third last week, fell seven spots to 10th after losses to TCU and Utah. UCLA remained No. 1, followed by UConn, South Carolina, Texas and LSU. USC, Maryland and Duke are next. Michael Andretti's Formula 1 dream comes to bittersweet fruition without his involvement Michael Andretti has been sidelined from his namesake motorsports organization and won’t have any role with the Formula 1 program he spent the last four years desperately trying to launch. His effort to get a program partnered with General Motors into F1 was approved last week, a month after he stepped aside from his teams. F1’s decision to expand its grid for Cadillac F1 came amidst a federal antitrust investigation into why Liberty Media refused to admit Andretti Global and after Andretti partners Dan Towriss and Mark Walter claimed controlling interest of the fledgling effort. Ryan Poles to remain Bears general manager and lead search for new head coach LAKE FOREST, Ill. (AP) — Chicago Bears president Kevin Warren said Ryan Poles will remain the general manager and serve as the point person in the search for a head coach to replace the fired Matt Eberflus. He says Poles will have the “final say” if the two have differing opinions on who should get the job. Chicago had never fired a coach during a season. But a six-game losing streak marked by questionable coaching decisions spurred the founding NFL franchise to change course. The Bears let Eberflus go Friday and replaced him on an interim basis with offensive coordinator Thomas Brown. Florida State hires Nebraska's Tony White as defensive coordinator, AP source says Florida State has hired Tony White to be its defensive coordinator after he developed consecutive top-20 defenses at Nebraska. That's according to a person familiar with the decision. The person spoke on condition of anonymity because neither the Seminoles nor Nebraska confirmed White’s move, which is pending a state background check. ESPN reported that White signed a three-year contract. White replaces Adam Fuller, who was fired last month. FSU coach Mike Norvell is trying to fill staff vacancies in hopes of salvaging a recruiting class. National Signing Day is Wednesday, with the transfer portal opening next week. Norvell also formally announced former UCF coach Gus Malzahn as his offensive coordinator.
As the rising star of cell therapy biotechs, Iovance Biotherapeutics (NASDAQ: IOVA) is a hot stock that's capturing a lot of attention, and for good reason. Iovance's one-of-a-kind medicine is already selling like hotcakes, and there's reason to believe that plenty more growth is on the way. Let's take a look at why this stock is worth purchasing today and never looking back. Start Your Mornings Smarter! Wake up with Breakfast news in your inbox every market day. Sign Up For Free » Today, Iovance has a trio of bullish drivers are the legs of the stock's investment thesis. A rapidly growing market First, Iovance's first cell therapy to be approved for sale, Amtagvi, is quickly finding its home in the market. This year, management estimates that sales of the therapy will bring in at least $160 million in revenue, with 2025's sum totaling at least $450 million. So investors who buy the stock soon will be, in theory, exposed to a tripling of the top line in the near term, which is bullish. In practice, the biotech is taking the actions needed to deliver on that ambitious goal for next year. Amtagvi is intended to treat patients who have advanced melanoma and who have already been treated with a common immunotherapy drug called pembrolizumab. Per management, its total addressable market is thus roughly between 20,000 and 30,000 patients annually. Serving those patients will require expanding the company's network of authorized treatment centers (ATCs). It's targeting a total of 70 ATCs in the U.S. before the end of the year, and progress is on track. Expanding manufacturing capability Another major initiative is expanding the company's manufacturing capacity for Amtagvi. Its current plans call for the expansion of one of its current facilities so it can generate doses for around 5,000 patients annually within the next few years, but it's also building up a network of contract manufacturers such that it can eventually treat an additional 15,000 patients per year. If those efforts are successful, it'll support Iovance's margins by controlling its cost of goods sold (COGS) . It might also be feasible for it to license out its facilities to produce cell therapies for other biopharma businesses, if it demonstrates exceptional competency in cell manufacturing. So the odds that Iovance will make good on its revenue estimates are decidedly favorable, and there's a clear runway for organic growth to continue after meeting them. A possible expansion of indications Finally, with a bit more research and development (R&D) work in the form of clinical trials testing Amtagvi in different oncology contexts, and in combination with pembrolizumab instead of only after a course of treatment, management thinks that it could one day treat as many as 70,000 patients with advanced melanoma globally. That'd expand its total addressable market by more than double, and likely require more manufacturing investments. Still, this is another bullish catalyst that is hard to ignore. The most important clinical trial is a study that's in phase 3 right now, investigating whether Amtagvi can be administered alongside pembrolizumab as a first line treatment. Being a first line treatment would lead to faster adoption of the therapy, rewarding shareholders in the process. The long haul could be even better Next year, Iovance will sync with regulators in Australia and Switzerland to see if they're willing to approve Amtagvi. It should also hear back from regulators in Canada, the U.K., and the E.U. in the same period, making for three potential catalysts and more revenue down the line. While it's true that there will be some lingering long-term execution risks relating to its cell manufacturing platform, the unique nature of its therapy means that it will likely retain the ability to draw on additional capital by taking out loans or issuing more shares of its stock. It'll probably need to do that before it becomes profitable at some point in the next few years. Nonetheless, as more and more patients globally gain access to Amtagvi, this company will have a lot of room to continue growing. Given Iovance's strong start to the therapy's commercialization, it's worth buying this stock. Don’t miss this second chance at a potentially lucrative opportunity Ever feel like you missed the boat in buying the most successful stocks? Then you’ll want to hear this. On rare occasions, our expert team of analysts issues a “Double Down” stock recommendation for companies that they think are about to pop. If you’re worried you’ve already missed your chance to invest, now is the best time to buy before it’s too late. And the numbers speak for themselves: Nvidia: if you invested $1,000 when we doubled down in 2009, you’d have $368,053 !* Apple: if you invested $1,000 when we doubled down in 2008, you’d have $43,533 !* Netflix: if you invested $1,000 when we doubled down in 2004, you’d have $484,170 !* Right now, we’re issuing “Double Down” alerts for three incredible companies, and there may not be another chance like this anytime soon. See 3 “Double Down” stocks » *Stock Advisor returns as of November 18, 2024 Alex Carchidi has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Iovance Biotherapeutics. The Motley Fool has a disclosure policy . Got $1,500? Buy Iovance Biotherapeutics Now and Don't Look Back was originally published by The Motley Fool
As the release date for "Uncharted 4" draws nearer, the excitement surrounding the game and its theatrical adaptation continues to build. With the promise of a captivating narrative, thrilling gameplay, and a cast of talented actors bringing the characters to life, "Uncharted 4" is shaping up to be a groundbreaking addition to the franchise that will surely leave a lasting impression on fans old and new.Manchester United have announced the signing of a 14-year-old talented midfielder sensation, who has been making waves in the grassroots football scene. The young prodigy has revealed that joining Manchester United is a dream come true for him, as he idolizes the legendary Red Devils midfielder, Paul Scholes.
Nebraska looks to stretch its season-long winning streak to five games when it hosts Southern on Monday night in Lincoln. The streak began after Michigan State crushed the Cornhuskers 89-52 in Nebraska's Big Ten opener on Dec. 7. Nebraska started the winning streak with an 85-68 home victory over Indiana to even its conference record at 1-1. Then the Cornhuskers (10-2) swept their way through the Diamond Head Classic in Honolulu, beating Murray State, host Hawaii and lastly Oregon State on Christmas Day to win the tournament championship. Nebraska coach Fred Hoiberg was pleased with the three double-digit victories in Hawaii, including the 78-66 win over the Beavers to earn the title. "The importance of winning three games against three quality teams, that's going to be help us down the road," Hoiberg said. Brice Williams scored 25 points on 9-of-13 shooting against Oregon State to cap a run that ended with earning tournament MVP. Williams tallied 32 points in the semifinal victory over Hawaii. He averaged 22 points, 3.7 rebounds, 3.0 assists and 2.0 steals in the tournament. Williams controlled the pace in the finale. "I was aggressive and wanted to let my defense lead my offense," Williams said. "I came out pretty hot and my team took it from there." Williams leads the Cornhuskers with a 19.7 scoring average. Juwan Gary (11.9 ppg) and Connor Essegian (11.8) are also scoring in double digits. Southern (5-7) is in the midst of a tough portion of its schedule and has been outscored by an average of 20 points during a three-game losing streak. The Jaguars started the skid by falling 74-61 at then-No. 17 Ole Miss on Dec. 17, then lost 89-73 at Loyola Marymount three days later. Southern was then mauled 82-51 at Southern California on Dec. 22. The Jaguars shot just 32.7 percent from the field against the Trojans and were a measly 2 of 19 from 3-point range. Southern coach Kevin Johnson said prior to the season that this stretch will help the team when it gets into SWAC play. "I feel we put together another strong schedule, that will challenge our team and give us some strong competition," Johnson said. "... We feel that this schedule will help us compete at the highest level going into SWAC play." Michael Jacobs is averaging a team-best 10.6 points, just ahead of Jordan Johnson's 10.4. Nebraska is 4-0 all-time against the Jaguars, including an 82-59 home win on Nov. 21, 2021, in the most recent meeting. --Field Level Media
Overall, this incident underscores the importance of vigilance in the face of online misinformation and the critical role of companies in defending their reputation and credibility against unfounded attacks. Lüde Group's handling of the situation sets a strong example for organizational integrity and resilience in the digital age.
Title: Montolivo: Conte Rarely Trusts Substitute Players, He Should Give Them More Playing TimeNone
As the situation gradually calmed down and tensions eased, efforts were made to reopen the closed food stall and restore normalcy in the canteen. The university administration, along with the Market Supervision Bureau, continued to monitor the situation closely to prevent any further disruptions and ensure the smooth operation of food stalls on campus.In conclusion, the upcoming releases of GTA 6 and NS2 are set to make next year a historic and unprecedented year in the world of gaming. With groundbreaking technology, innovative gameplay mechanics, and a dedicated fan base, these games are poised to set new standards and redefine the gaming landscape. Gamers and analysts alike are eagerly awaiting the arrival of these highly anticipated titles and are already counting down the days until they can get their hands on them. 2022 is shaping up to be a year like no other in the world of gaming, and fans can look forward to unforgettable experiences and countless hours of gaming enjoyment.
In the world of football, goalkeepers play a crucial role in the success of a team. Chelsea, currently one of the most dominant teams in the English Premier League, has been making waves with their exceptional attacking capabilities. And in the midst of all this success, one player has stood out as their perfect goalkeeping choice - Aaron Ramsdale.Apple Stock Today: A Rise In Volatility Would Generate Profits In This Options TradeLifestance Health group director Robert Bessler sells $565,500 in stock
In recent reports from English media, it has been revealed that Manchester United has not yet discussed the possibility of selling their star forward Marcus Rashford. The news comes amidst speculation about Rashford's future at the club following a mixed season for the young Englishman. Despite facing criticism for his form and consistency, it seems that Manchester United's hierarchy, led by manager Amorim, remain satisfied with Rashford and his contributions to the team.Deficit soars as Biden heads out the doorManchester United fans can look forward to the return of Victor Lindelof in the upcoming Europa League match this midweek, as the Swedish defender edges closer to making his comeback from injury. However, there is still uncertainty surrounding the return dates for Jonny Evans and Luke Shaw, according to recent reports.