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CARLSBAD, Calif. , Dec. 12, 2024 /PRNewswire/ -- Ourself, a leader in the next generation of skincare, today announced that clinical data evaluating Ourself's patented delivery technology, Tiered-Release VesiclesTM (TRVs), was published in Dermatologic Surgery , the official journal of the American Society for Dermatologic Surgery. The publication highlights that TRVs have the potential to revolutionize skincare by enabling the delivery of large, bioactive molecules directly into the epidermis and dermis. The Ourself delivery method promises to reshape the way we care for our skin and opens new possibilities for enhancing cosmetic outcomes topically. "Publication of this data reinforces that Ourself is setting a new standard in topical delivery," said Jim Hartman , Ourself's Chief Executive Officer. "We are excited to lead these advancements and look forward to the growth and innovation this breakthrough will inspire for our brand and the industry as a whole." "Tiered-Release Vesicles represent a revolutionary advancement in dermal delivery technology, addressing a stagnation in the industry that has persisted for over four decades," said Ashish C. Bhatia , MD, FAAD, author and board-certified dermatologist and Mohs surgeon at Oak Dermatology. For decades, the skin's outermost layer, the stratum corneum, has long been a barrier that limits the effectiveness of skincare products, blocking essential ingredients from reaching deeper layers. Traditional delivery systems like liposomes have failed to penetrate deeply enough to achieve substantial results—TRVs change this paradigm. "It's not just about the ingredients but also how the ingredients get to where they need to go. Ourself is revolutionary and a game changer in our industry because we've had the same delivery systems for 40 years. Now we have something better," said Amy B. Lewis , MD, board-certified dermatologist at Lewis Dermatology and Associates. "The Tiered-Release Vesicle delivery system is a major step forward for skincare. These developments redefine what is now achievable in topical delivery, unlocking limitless potential for the future of skincare," said Amir Moradi , MD, MBA lead author and double board-certified facial plastic and otolaryngology-head and neck surgeon at Moradi MD. ABOUT OURSELF Leveraging decades of biotech and skincare expertise, Ourself developed a new, scientifically advanced delivery technology to broaden the capabilities of cosmetic skincare forever. Utilizing patented Tiered-Release VesiclesTM, Ourself "hero" products ensure deep ingredient delivery, sending larger molecules, powerful peptides and all-in-one formulations directly to the layer of the skin where they're needed most to improve loss of volume, lines & wrinkles, and uneven pigmentation. Ourself developed the first non-injectable Lip Filler clinically proven to restore volume by delivering two sizes of hyaluronic acid into the lips, topically. Ourself is based in Carlsbad, CA. For more information, visit Ourself.com . REFERENCE: Moradi A, et al. In Vivo and Ex Vivo Evaluation of a Novel Method for Topical Delivery of Macromolecules Through the Stratum Corneum for Cosmetic Applications. Dermatol Surg. 2024 SOURCE OurselfTheir ages vary. But a conspicuous handful of filmmaking lions in winter, or let’s say late autumn, have given us new reasons to be grateful for their work over the decades — even for the work that didn’t quite work. Which, yes, sounds like ingratitude. But do we even want more conventional or better-behaved work from talents such as Francis Ford Coppola? Even if we’re talking about “Megalopolis” ? If Clint Eastwood’s “Juror #2” gave audiences a less morally complicated courtroom drama, would that have mattered, given Warner Bros.’ butt-headed decision to plop it in less than three dozen movie theaters in the U.S.? Coppola is 85. Eastwood is 94. Paul Schrader, whose latest film “Oh, Canada” arrives this week and is well worth seeking out, is a mere 78. Based on the 2021 Russell Banks novel “Foregone,” “Oh, Canada” is the story of a documentary filmmaker, played by Richard Gere, being interviewed near the end of his cancer-shrouded final days. In the Montreal home he shares with his wife and creative partner, played by Uma Thurman, he consents to the interview by two former students of his. Gere’s character, Leonard Fife, has no little contempt for these two, whom he calls “Mr. and Mrs. Ken Burns of Canada” with subtle disdain. As we learn over the artful dodges and layers of past and present, events imagined and/or real, Fife treats the interview as a final confession from a guarded and deceptive soul. He’s also a hero to everyone in the room, famous for his anti-Vietnam war political activism, and for the Frederick Wiseman-like inflection of his own films’ interview techniques. The real-life filmmaker name-checked in “Oh, Canada” is documentarian Errol Morris, whose straight-to-the-lens framing of interview subjects was made possible by his Interrotron device. In Schrader’s adaptation, Fife doesn’t want the nominal director (Michael Imperioli, a nicely finessed embodiment of a second-rate talent with first-rate airs) in his eyeline. Rather, as he struggles with hazy, self-incriminating memories of affairs, marriages, one-offs with a friend’s wife and a tense, brief reunion with the son he never knew, Fife wants only his wife, Emma — his former Goddard College student — in this metaphoric confessional. Schrader and his editor Benjamin Rodriguez Jr. treat the memories as on-screen flashbacks spanning from 1968 to 2023. At times, Gere and Thurman appear as their decades-young selves, without any attempt to de-age them, digitally or otherwise. (Thank god, I kind of hate that stuff in any circumstance.) In other sequences from Fife’s past, Jacob Elordi portrays Fife, with sly and convincing behavioral details linking his performance to Gere’s persona. We hear frequent voiceovers spoken by Gere about having ruined his life by age 24, at least spiritually or morally. Banks’ novel is no less devoted to a dying man’s addled but ardent attempt to come clean and own up to what has terrified him the most in the mess and joy of living: Honesty. Love. Commitment. There are elements of “Oh, Canada” that soften Banks’ conception of Fife, from the parentage of Fife’s abandoned son to the specific qualities of Gere’s performance. It has been 44 years since Gere teamed with Schrader on “American Gigolo,” a movie made by a very different filmmaker with very different preoccupations of hetero male hollowness. It’s also clearly the same director at work, I think. And Gere remains a unique camera object, with a stunning mastery of filling a close-up with an unblinking stillness conveying feelings easier left behind. The musical score is pretty watery, and with Schrader you always get a few lines of tortured rhetoric interrupting the good stuff. In the end, “Oh, Canada” has an extraordinarily simple idea at its core: That of a man with a movie camera, most of his life, now on the other side of the lens. Not easy. “I can’t tell the truth unless that camera’s on!” he barks at one point. I don’t think the line from the novel made it into Schrader’s script, but it too sums up this lion-in-winter feeling of truth without triumphal Hollywood catharsis. The interview, Banks wrote, is one’s man’s “last chance to stop lying.” It’s also a “final prayer,” dramatized by the Calvinist-to-the-bone filmmaker who made sure to include that phrase in his latest devotion to final prayers and missions of redemption. “Oh, Canada” — 3 stars (out of 4) No MPA rating (some language and sexual material) Running time: 1:34 How to watch: Opens in theaters Dec. 13, running 1in Chicago Dec. 13-19 at the Gene Siskel Film Center, 164 N. State St.; siskelfilmcenter.org Michael Phillips is a Tribune critic.
Students work diligently to finish the semester’s projects and study for finals. People throughout the region decorate their homes and businesses for the season and search for the perfect gifts for loved ones as the holidays approach. East Tennessee State University is gearing up for the biggest day of the semester – Commencement – but offers plenty of additional activities for students and the community in the month of December! The following listing includes events that are open to the public and are free unless otherwise noted: Music ETSU BLUE Down Home Takeover December 2-6, 7 p.m. each evening – Down Home, 300 W. Main Street This five-night musical event showcases all the bands in ETSU’s Bluegrass, Old-Time and Roots Music Studies program, which includes not only bluegrass and old-time ensembles, but country, a cappella and Celtic groups, as well. Tickets are $15 at the door; ETSU students with ID receive a discount. Holiday Concert: ‘For Auld Lang Syne’ December 7, performances at 4 p.m. and 7:30 p.m. – ETSU Foundation Grand Hall, Martin Center for the Arts Over 250 performers will take part in this beloved ETSU holiday tradition, including the ETSU Chorale, BucsWorth, East Tennessee Belles, Greyscale, Ascension, Percussion Ensemble and Faculty Brass Quintet, along with special guests Matthew Fisher, organ, and Joanna Seiber, harp. Tickets are $15-$25; free for ETSU students with ID. Theater/Cinema Bud Frank Cinema First Friday Screening: ‘Flow’ December 6, 7 p.m. – Bud Frank Theatre, Gilbreath Hall The Bud Frank Cinema’s First Friday Screening on Dec. 6 is “Flow,” a 2024 French film which opens for wide release the same day. “A wondrous journey, through realms natural and mystical, ‘Flow’ follows a courageous cat after his home is devastated by a great flood.” Bud Frank Cinema Film Screening: ‘Seven Samurai’ December 13, 7 p.m. – Bud Frank Theatre, Gilbreath Hall The Bud Frank Cinema and Tri-City Film Farm present a restoration of “Seven Samurai,” a 1954 film from Japan that tells the story of a 16 th -century village whose desperate inhabitants hire seven samurai warriors to protect them from invading bandits. ‘A Charlie Brown Christmas: Live on Stage’ December 17, 7 p.m. – ETSU Foundation Grand Hall, Martin Center for the Arts The timeless, award-winning animated television special by Charles M. Schulz comes to life in this faithful stage adaptation the whole family can enjoy. After the final bow, the audience is invited to join the Peanuts gang in singing traditional Christmas songs and carols. Tickets are $49.50-$139; limited seating is available. Fine Arts ‘FL3TCH3R Exhibit: Social and Politically Engaged Art’ Continuing through December 6, 9 a.m.-4:30 p.m. Monday-Friday – Reece Museum This annual exhibit, renowned for its exploration of contemporary social and political movements, features a diverse array of artworks addressing pressing global issues. ‘Stitch Together: The Social Seamstress in Southern Appalachia’ Continuing through January 10, 2025, 9 a.m.-4:30 p.m. Monday-Friday – Reece Museum The Reece Museum hosts this exhibit exploring the social connections of seamstresses by showcasing the fashion and clothing of the museum’s permanent collection. Holiday Fun and More Ice Skating at ETSU Various hours, Thursdays-Sundays through December 21 – University Commons ETSU’s beloved synthetic ice skating rink is open for the holiday season. This year, in partnership with Brightspeed, the rink is free to ETSU students, faculty and staff with valid ID and open to the community with a $5 skate rental for all ages. Hours are Thursdays and Fridays from 5-9 p.m., Saturdays from noon-7 p.m., and Sundays from 2-7 p.m. Great Lecture Series December 6, 2 p.m. – East Tennessee Room, D.P. Culp Student Center The Great Lecture Series celebrates and showcases ETSU faculty who have recently been promoted to full professor, giving them an opportunity to share their work with the broader community. Attendees of this installment will hear from Drs. Brian Johnston, John Rankin and Megan Quinn. Jacob’s Nature Park: As We See It! December 7, 1-2:30 p.m. – Jacob’s Nature Park at Sinking Creek, 1919 Ocala Street This event for the community features five 15-minute presentations by ETSU students on park-specific topics, such as poisonous plants, mushroom coolness, pollinator trivia and more. Interactive activities, games, giveaways and hands-on learning opportunities for all ages are included. ETSU Fall Commencement December 14, 10 a.m. and 2:30 p.m. – Ballad Health Athletic Center (Mini-Dome) ETSU celebrates its fall 2024 graduating class in two ceremonies (10 a.m. – Quillen College of Medicine, College of Public Health, College of Health Sciences and College of Arts and Sciences; and 2:30 p.m. – Clemmer College of Education and Human Development, College of Business and Technology and College of Nursing). Complete information for graduating students, guests and faculty is available on the Commencement website, etsu.edu/commencement , where livestreaming will be offered for those not attending in person. ETSU Alumni Arctic Adventures: Frost and Fun Skate Night December 19, 5-8:30 p.m. – University Commons The ETSU Alumni Association presents an evening of Frost and Fun at the ETSU synthetic ice skating rink sponsored by Brightspeed. Participants can enjoy popcorn and hot cocoa inside the first-floor lobby of the D.P. Culp Student Center, as well as limited-edition T-shirts, a visit from Bucky, giveaways and holiday music. To learn more about these and other events happening at ETSU, visit the university’s online calendar at etsu.edu/calendar/default.php . For disability accommodations, contact Disability Services at (423) 439-8346.WASHINGTON (AP) — In the two weeks since Donald Trump won the presidency, he's tried to demonstrate his dominance by naming loyalists for top administration positions, even though many lack expertise and some face sexual misconduct accusations. It often seems like he's daring Congress to oppose his decisions. But on Thursday, Trump's attempt to act with impunity showed a crack as Matt Gaetz , his choice for attorney general, withdrew from consideration. Trump had named Gaetz, a Florida congressman, to be the country's top law enforcement official even though he was widely disliked by his colleagues, has little legal experience and was accused of having sex with an underage girl, an allegation he denied. After being plagued by investigations during his first presidency, Trump wanted a devoted ally in charge of the Justice Department during his second. However, it was never obvious that Gaetz could win enough support from lawmakers to get confirmed. Now the question is whether Gaetz was uniquely unpalatable, or if Trump's other picks might exceed his party's willingness to overlook concerns that would have sunk nominees in a prior political era. The next test will likely be Pete Hegseth, who Trump wants to lead the Pentagon despite an allegation of sexual assault that he's denied. Sen. Thom Tillis, a North Carolina Republican who serves on the Senate Judiciary Committee, said the controversy over Gaetz would have little bearing on Trump’s choices for other positions. “One at a time,” he said. Sen. Richard Blumenthal, a Connecticut Democrat, suggested otherwise, claiming “the dominoes are falling.” “The drip drip of evidence and truth is going to eventually doom some others,” he said. Trump's election victory was a sign that there may not be many red lines left in American politics. He won the presidential race despite authoritarian, racist and misogynist rhetoric, not to mention years of lies about election fraud and his role in sparking the Jan. 6, 2021, attack on the U.S. Capitol. He was also criminally convicted of falsifying business records to pay hush money, and he was found liable for sexual abuse in a civil case. Empowered by voters who looked past his misconduct and saw him as a powerful agent of change, Trump has shown no deference to Washington norms while working to fill his second administration . Although some of his personnel choices have extensive experience in the areas they've been chosen to lead, others are personal friends and Fox News personalities who have impressed and flattered Trump over the years. Several have faced allegations involving sexual misconduct . Hegseth, an Army veteran and Fox News host, is facing the most scrutiny after Gaetz. Once Trump announced Hegseth as his nominee for Pentagon chief, allegations emerged that he sexually assaulted a woman in California in 2017. The woman said he took her phone, blocked the door to the hotel room and refused to let her leave, according to a police report made public this week. Hegseth told police at the time that the encounter had been consensual and denied any wrongdoing, the report said. However, he paid the woman a confidential settlement in 2023. Hegseth's lawyer said the payment was made to head off the threat of a baseless lawsuit. Trump’s choice for secretary of health and human services, Robert F. Kennedy Jr., has faced allegations of misconduct too. A woman who babysat for him and his second wife told Vanity Fair magazine that Kennedy groped her in the late 1990s, when she was 23. Kennedy did not deny the allegation and texted an apology to the woman after the article was published. That isn't the only hurdle for Kennedy; he's spent years spreading misinformation and conspiracy theories about vaccines, raising fears about making him a top health official in the new administration. Linda McMahon, chosen by Trump to be education secretary, is fighting a lawsuit connected to her former company, World Wrestling Entertainment. She’s accused of knowingly enabling sexual exploitation of children by an employee as early as the 1980s, and she denies the allegations. Tulsi Gabbard is another person who could face a difficult confirmation battle, but for very different reasons. The former Democratic representative from Hawaii has been a vocal Trump ally, and he chose her to be national intelligence director. But there's grave concern by lawmakers and national security officials over Gabbard’s history of echoing Russian propaganda. Critics said she would endanger relationships with U.S. allies. Gaetz was investigated by federal law enforcement for sex trafficking, but the case was closed without charges and Republicans have blocked the release of a related report from the House Ethics Committee. However, some allegations leaked out, including that Gaetz paid women for sex. One of the women testified to the committee that she saw Gaetz having sex with a 17-year-old girl, according to a lawyer for the woman. As Gaetz met with senators this week, it became clear that he would face stubborn resistance from lawmakers who were concerned about his behavior and believed he was unqualified to run the Justice Department. “While the momentum was strong, it is clear that my confirmation was unfairly becoming a distraction,” Gaetz wrote on social media when announcing his withdrawal. Sen. Mike Braun, an Indiana Republican, said he believed there were four to six members of the caucus who would have voted against Gaetz, likely dooming his nomination, and “the math got too hard.” He said some of the issues and allegations around Gaetz were “maybe beyond the pale." “I think there were just too many things, it was like a leaky dike, and you know, it broke," Braun said. Trump thanked Gaetz in a post on Truth Social, his social media website, without addressing the substance of the allegations against him. “He was doing very well but, at the same time, did not want to be a distraction for the Administration, for which he has much respect,” Trump wrote. ____ Associated Press writers Mary Clare Jalonick, Stephen Groves and Lisa Macaro contributed from Washington. Jill Colvin in New York and Adriana Gomez Licon in Fort Lauderdale, Florida, also contributed. Chris Megerian And Colleen Long, The Associated PressTiny robot from Amazon will be your child's cool but sometimes annoying friend
People's financial services CEO sells $142,536 in stock
Martinez parades goalkeeper awards and justifies them with wonder save for Villa in Champions LeagueNo. 10 Georgia scores nearly at will, destroys UMassMore than 1,000 victims of the DKZ Technologies fraud gathered in Hyderabad on Thursday demanding fair investigation into the case. The victims discussed the concerns with their advocate Aashir Khan and also interacted with the media. This comes over 2.5 months after company’s managing director Ashfaq Rahil and his wife and company’s director Syeda Aisha Naz were arrested by the Central Crime Station (CCS) of Hyderabad. A case was booked against the firm on September 14, 2024 following a complaint from Dr. Abul Jaish of Mehdipatnam - in which he stated that he had invested ₹2.74 crore in August 2024. The complainant alleged that the company lured investors with promises of high returns on investments and stopped paying the same after an initial stint. “We are not satisfied with the investigation being carried out by the Hyderabad CCS. We request the Central Bureau of Investigation (CBI) or the Enforcement Directorate (ED) to take up the investigation. Over 18,000 investors, including doctors and lawyers, from 3-4 Indian cities, and other countries, including Saudi Arabia and Canada, have reported losses between ₹500 crore and ₹700 crore. However, the amount recovered is a mere ₹5 crore,” said Mohd Shahbaz, one of the victims. The victims alleged that of the 38 accused who include popular YouTubers like Nabeel Afridi, Kirak Khala among others, only four were arrested so far and they were being “treated like VIPs”. As the company office shut down and the owners went incommunicado, hundreds of investors staged a protest and approached the Madhapur police in September. Published - December 27, 2024 12:25 am IST Copy link Email Facebook Twitter Telegram LinkedIn WhatsApp Reddit
To play Maria Callas, Angelina Jolie had to learn how to breathe again
