CAMP4 Reports Third Quarter 2024 Financial ResultsPreview: Ipswich Town vs. Bournemouth - prediction, team news, lineups

- Completed Initial Public Offering (IPO) of common stock, raising gross proceeds of $82.1M - Single Ascending Dose (SAD) portion of Phase 1 study of CMP-CPS-001 completed; safety data anticipated in Q1 2025 - Entered strategic research collaboration with BioMarin valued at over $370M CAMBRIDGE, Mass., Nov. 21, 2024 (GLOBE NEWSWIRE) -- CAMP4 Therapeutics Corporation (“CAMP4”) (Nasdaq: CAMP), a clinical-stage biotechnology company developing a pipeline of regRNA-targeting therapeutics designed to upregulate gene expression with the goal of restoring healthy protein levels across a range of genetic diseases, today reported financial results for the third quarter ended September 30, 2024, and provided a corporate update. “The third quarter of 2024 has been transformational for CAMP4, highlighted by our successful IPO and continued strong progress with our lead program, CMP-CPS-001, which received Orphan Drug Designation and Rare Pediatric Disease Designation from the FDA, underscoring its potential as a novel therapeutic candidate for the treatment of urea cycle disorders,” said Josh Mandel-Brehm, Chief Executive Officer of CAMP4. “We also partnered with BioMarin to identify novel therapeutics targeting regRNAs associated with genetic diseases, validating the potential of our RNA Actuating Platform and reinforcing our commitment to advance cutting-edge solutions for patients in need.” Mr. Mandel-Brehm continued, “We continue to advance our CMP-CPS-001 program through the Phase 1 trial, and we anticipate reporting SAD safety data in the first quarter of 2025 followed by multiple ascending dose (MAD) biomarker efficacy data in the second half of 2025, that may enable a registrational Phase 2/3 study. With the proceeds from our IPO, we are well positioned to support continued clinical and preclinical development of our ongoing programs.” Recent Corporate Highlights: In October 2024, CAMP4 completed its IPO of 6,820,000 shares of its common stock at an initial public offering price of $11.00 per share. Aggregate gross proceeds to CAMP4 were approximately $75.0 million. The underwriters also partially exercised their option to purchase an additional 643,762 shares of common stock for total offering gross proceeds of $82.1 million. Entered strategic research collaboration agreement with BioMarin to leverage CAMP4’s RAP PlatformTM to identify and advance regRNAs for rare genetic conditions. CAMP4 is eligible to receive upfront and milestone payments in addition to tiered royalties. The FDA granted RPDD and ODD to CMP-CPS-001 for the treatment of UCDs. Ongoing Phase 1 clinical trial of CMP-CPS-001 in UCDs, with dosing completed for all SAD cohorts. The Phase 1 study is a randomized, double-blind, and placebo-controlled study designed to evaluate the safety, tolerability, and pharmacokinetics of CMP-CPS-001 in 96 healthy volunteers. The company anticipates reporting SAD safety data in the first quarter of 2025 followed by MAD safety, pharmacokinetic and pharmacodynamic biomarker efficacy data in the second half of 2025. Third Quarter 2024 Financial Results CAMP4 ended the third quarter with $2.5 million in cash and cash equivalents. On a pro forma basis, considering the $82.1M IPO proceeds, the company is well positioned to support continued growth and the development of its ongoing programs. Research and Development (R&D) expenses were $9.7 million for the third quarter of 2024 compared to $9.8 million for the third quarter of 2023. The decrease was mainly due to a modest reduction in workforce-related expense, offset in part by an increase in lab operation expense and preclinical and clinical consulting fees. General and administrative (G&A) expenses were $3.8 million for the quarter ended September 30, 2024, compared to $2.9 million for the quarter ended September 30, 2023. The increase in G&A expenses was primarily due to an increase in stock-based compensation expense and higher patent-related expenses vs. prior period. Net loss was $13.5 million for the third quarter 2024, compared to $11.7 million for the same period in 2023. About CAMP4 Therapeutics CAMP4 is developing disease-modifying treatments for a broad range of genetic diseases where amplifying healthy protein may offer therapeutic benefits. Our approach amplifies mRNA by harnessing a fundamental mechanism of how genes are controlled. To amplify mRNA, our therapeutic ASO drug candidates target regRNAs, which act locally on transcription factors and are the master regulators of gene expression. CAMP4’s proprietary RAP PlatformTM enables the mapping of regRNAs and generation of therapeutic candidates designed to target the regRNAs associated with genes underlying haploinsufficient and recessive partial loss-of-function disorders, of which there are more than 1,200, in which a modest increase in protein expression may have the potential to be clinically meaningful. Learn more about us at www.CAMP4tx.com and follow us on LinkedIn and X . Forward-Looking Statements This press release contains forward-looking statements which involve risks, uncertainties and contingencies, many of which are beyond the control of the Company, which may cause actual results, performance, or achievements to differ materially from anticipated results, performance, or achievements. All statements other than statements of historical facts contained in this press release are forward-looking statements. In some cases, you can identify forward-looking statements by terms such as “may,” “will,” “should,” “expect,” “plan,” “anticipate,” “could,” “intend,” “target,” “project,” “contemplate,” “believe,” “estimate,” “predict,” “potential” or “continue” or the negative of these terms or other similar expressions, although not all forward-looking statements contain these words. Forward-looking statements include, but are not limited to, statements concerning CAMP4’s plans, objectives, expectations and intentions; the timing and results of ongoing and future clinical trials, including expectations on the timing of reporting SAD and MAD data from and seeking regulatory approval for the CMP-CPS-001 trial; its growth strategy; and cash balance guidance. The forward-looking statements in this press release speak only as of the date of this press release and are subject to a number of known and unknown risks, uncertainties and assumptions that could cause the Company’s actual results to differ materially from those anticipated in the forward-looking statements, including, but not limited to: the Company’s limited operating history, incurrence of substantial losses since the Company’s inception and anticipation of incurring substantial and increasing losses for the foreseeable future; the Company’s need for substantial additional financing to achieve the Company’s goals; the uncertainty of clinical development, which is lengthy and expensive, and characterized by uncertain outcomes, and risks related to additional costs or delays in completing, or failing to complete, the development and commercialization of the Company’s current product candidates or any future product candidates; delays or difficulties in the enrollment and dosing of patients in clinical trials; the impact of any significant adverse events or undesirable side effects caused by the Company’s product candidates; potential competition, including from large and specialty pharmaceutical and biotechnology companies; the Company’s ability to realize the benefits of the Company’s current or future collaborations or licensing arrangements and ability to successfully consummate future partnerships; the Company’s ability to obtain regulatory approval to commercialize any product candidate in the United States or any other jurisdiction, and the risk that any such approval may be for a more narrow indication than the Company seeks; the Company’s dependence on the services of the Company’s senior management and other clinical and scientific personnel, and the Company’s ability to retain these individuals or recruit additional management or clinical and scientific personnel; the Company’s ability to grow the Company’s organization, and manage the Company’s growth and expansion of the Company’s operations; risks related to the manufacturing of the Company’s product candidates, which is complex, and the risk that the Company’s third-party manufacturers may encounter difficulties in production; the Company’s ability to obtain and maintain sufficient intellectual property protection for the Company’s product candidates or any future product candidates the Company may develop; the Company’s reliance on third parties to conduct the Company’s preclinical studies and clinical trials; the Company’s compliance with the Company’s obligations under the licenses granted to the Company by others, for the rights to develop and commercialize the Company’s product candidates; risks related to the operations of the Company’s suppliers; and other risks and uncertainties described in the section “Risk Factors” in the Company’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2024, as well as other information we file with the Securities and Exchange Commission. The forward-looking statements in this press release are inherently uncertain and are not guarantees of future events. Because forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted or quantified and some of which are beyond the Company’s control, you should not unduly rely on these forward-looking statements. The events and circumstances reflected in the forward-looking statements may not be achieved or occur and actual future results, levels of activity, performance and events and circumstances could differ materially from those projected in the forward-looking statements. Moreover, the Company operates in an evolving environment. New risks and uncertainties may emerge from time to time, and management cannot predict all risks and uncertainties. Investors, potential investors, and others should give careful consideration to these risks and uncertainties. Except as required by applicable law, the Company does not undertake to publicly update or revise any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances or otherwise. Contacts Investor Relations: Sandya von der Weid LifeSci Advisors svonderweid@lifesciadvisors.com Media: Jason Braco, Ph.D. LifeSci Communications jbraco@lifescicomms.com (1) Working capital is defined as total current assets less total current liabilities. See our condensed consolidated financial statements and the related notes thereto included in our Quarterly Report on Form 10-Q for the period ended September 30, 2024 for further details regarding our current assets and current liabilities.Scheffler goes on a run of birdies in the Bahamas and leads by 2

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Paris stocks rally as Macron fights on, jobs data boosts Wall StreetOf the many countries of the Global South that maintain cordial ties with Russia, Iran happens to be one of the few outliers where the public doesn’t hold predominantly positive views of the Eurasian heavyweight. Anti-Russia sentiments have snowballed in Iran since the start of the Ukraine war, and as reflected in an October 2022 Cambridge University study , unfavorable perceptions of Russia are more widespread in Iran than in Bulgaria, Egypt, Saudi Arabia, North Macedonia or Armenia. The sympathy of a sizable portion of Iranian society with Ukraine as it fights a war that NATO leaders have described as a confrontation between the West and the rest, is a surprising finding given the government’s unchanged resolve to sustain a foreign policy built on opposition to the Western powers, especially the United States. It might also be unexpected for Ukrainian President Volodymyr Zelenskyy. As he seeks to diversify his lineup of benefactors, Zelenskyy has lost sight of a contingent of sympathizers in Iran sticking up for his country despite the two nations not having a lot in common culturally and historically. The spillover effects of the war are also unlikely to have reverberations in the daily lives of Iranians, rendering their sympathies even more authentic. In the initial stages of Russia’s deadly campaign, voices from Iran’s intelligentsia condemning Vladimir Putin were common and posed a challenge to the state narrative that openly downplayed Russia’s atrocities. Yet the Islamic Republic emerged as a consistent provider of military support to Russia. From the beginning of the full-scale invasion through September 13 this year, Russia has fired 8,060 Iran-made Shahed drones at Ukraine. Over time, Zelenskyy escalated his Iran-bashing rhetoric, culminating in remarks in October, when he called Iran, China and North Korea a “coalition of criminals.” To be sure, Zelenskyy’s skepticism of Iran had begun to surface after the Islamic Revolutionary Guard Corps (IRGC) downed the Ukraine International Airlines flight PS752 on January 8, 2020, killing 176 passengers and crew. The Islamic Republic made a bad situation worse by denying wrongdoing for three days and then refusing to investigate the case. After Russia started the war, Zelenskyy was largely focused on strategizing national mobilization and an effective defense against the aggressor. As Tehran sought to ingratiate itself with Moscow, the Ukrainian leader upped the ante against Iran piecemeal. One of his first periodic Twitter (X) castigations of Iran was a message on Nov 6, 2022, when he wrote he had “discussed increasing sanctions & opposing actions of Iran, which supports aggression” in a meeting with the President of the European Commission Ursula von der Leyen. It is not surprising that he intensified his opprobrium of Iran to draw attention to the alliance of Tehran and Moscow, which has damaged his war effort. But the flip side has been that he fell out of favor with many Iranians who otherwise championed his cause. Zelenskyy has nurtured a public aversion to Iran, which can be beneficial domestically from a rally-round-the-flag point of view, but it is also alienating potential companions. When the Ukrainian powerlifter Ivan Chuprinko refused to shake hands with his Iranian opponent Amir Reza Mesforoosh during the International Powerlifting Federation world championship awards ceremony in Sun City, South Africa, last May, a large chorus of Iranians criticized what they said was his unsporting conduct. Several social media users accused Zelenskyy of being ignorant about the reality of Iran and agitating his people against the wrong enemy. The Ukrainian president, who has crisscrossed countries far and wide to enlist support for his people, hasn’t shied away from appealing to undemocratic leaders who hadn’t shown any inclination to denounce Russia or aid Ukraine. In June of this year, he traveled to Jeddah to meet the Saudi Crown Prince Mohammed bin Salman, despite the kingdom’s longstanding affinity with Russia, including their more recent coordination to stabilize the energy market with Iran’s output being excluded due to the sanctions. Zelenskyy also phoned the United Arab Emirates (UAE) leadership several times, courting the Persian Gulf kingdom after it abstained from voting on a February 2022 Security Council resolution censuring Russia’s aggression. UAE had also refused to vote in favor of a UN General Assembly resolution suspending Russia’s membership in the UN Human Rights Council and another nonbinding resolution calling on Russia to pay war reparations to Ukraine. But with Iran, where a spontaneous outpouring of pro-Ukraine solidarity had markedly distinguished the mood of the country from its neighbors, Zelenskyy has shut the door to diplomacy. His impatience with Tehran supplying weaponry to Moscow has foreclosed the possibility of engagement, even with a new president inaugurated in Tehran. In October 2022, in one of his early decisions to drive home his anger at the Islamic Republic, Zelenskyy expelled scores of Iranian students studying in Ukraine, revoking their government scholarships. There’s little clarity as to how many students were removed, but those who shared their stories with the media recounted being accosted and chastised by Ukraine’s immigration officers. Targeting one of the most vulnerable demographics — students untethered from the politics of their government — was not the smartest idea for low-cost muscle-flexing. In doing so, Zelenskyy glossed over decades of economic and academic partnership between the two countries, one that bloomed whenever pro-reform administrations were in power in Iran. Under the former President Hassan Rouhani, for example, several Iranian and Ukrainian universities had developed joint projects and student exchange programs. In one case, the Kharkiv National Medical University had signed cooperation agreements with five major Iranian universities. During a trip to Ukraine by the other former reformist president of Iran, Mohammad Khatami, in October 2002 to meet his counterpart Leonid Kuchma, the two leaders signed an agreement on setting up an airplane construction consortium. The first Antonov-140 regional airliners were licensed to be manufactured at the HESA facility in the Iranian city of Isfahan in 1996, and the Islamic Republic was eyeing an even closer industrial collaboration. There have been points in time when Ukraine’s trade surplus with Iran was even greater than its trade balance with Saudi Arabia and the UAE. In 2016, shortly after the nuclear deal normalized international trade with Iran, it became one of Ukraine’s top 15 trading partners . However, Zelenskyy’s initiative in May 2023, enforcing economic sanctions that prohibited trade between the two countries for the next 50 years will compromise these links and likely fail to bring about any win-win outcome. In a span of 50 years, all sorts of fundamental political changes can occur in Iran, and it is not a stretch to describe the decision by Kiev, with all the sweeping impacts it can have, as a spur-of-the-moment reaction to the current downturn in bilateral relations. To be sure, Russia’s full-scale invasion has made some existing political and security alliances more explicit and unfiltered than before. Russia’s traditional partners condoned its military expedition, rationalizing the war as either acceptable or inevitable. Nations that have traditionally been part of the Western political orbit sided with Ukraine, even if they previously lacked close ties with the Eastern European nation. Under its now-deceased president Ebrahim Raisi, Iran didn’t hesitate to pledge allegiance to the aggressor. Raisi picked up the phone to call Putin hours after the invasion began, deploring NATO’s eastward expansion and committing support for Moscow. He said he hoped “what is happening ends up to benefit the nations and the region.” As a neophyte politician, the hardline jurist was inordinately dependent on Putin to carve out a foothold on the world stage. As his administration actively antagonized Europe, Raisi was left with few options, and his outreach to Russia often seemed obedient as much as it was preordained. In his three years as president, Raisi never traveled to any European country, and didn’t receive any European leader in Tehran — other than Alexander Lukashenko of Belarus. And he oversaw day-to-day microaggressions in relations with the European Union, a case in point being the closure of the French cultural center in Tehran in 2023 after a skirmish with the government of Emmanuel Macron. Upon Raisi’s first Moscow visit on January 19, 2022, for an audience with his Russian counterpart, the lukewarm reception at the Kremlin took even the hardliners in Tehran aback. What was described as a state visit wound up being a diplomatic faux pas: the guard of honor was missing; Putin didn’t even leave his room to greet the visiting dignitary, and eventually met him at his famous “long table.” Lastly, there was even no trace of the two nations’ flags in an event that ended without a press conference. The Islamic Republic understood that it was too vulnerable to dispute the absence of these optional niceties. On a different note, even after Russia threw its weight behind the United Arab Emirates on two occasions in 2023, signing statements that questioned Iran’s sovereignty of three islands in the Persian Gulf claimed by UAE, there wasn’t much that the Islamic Republic could do. It was a fait accompli — being let down by a power that was supposed to be an ally. The broader public, however, has been skeptical of embracing Russia, even for a lack of alternatives. Owing to a blend of historical grievances and new fault lines, perceptions of Russia among Iranians have been deteriorating steadily. A 2022 survey by the Alliance of Democracies Foundation showed 50 percent of Iranian people had negative views toward Russia. Only 15 percent said they viewed Russia’s influence favorably. One catalyst of the lingering bitterness is Russia’s imperial footprint during the 19 th century, when it annexed large swaths of Iran’s territory through a trio of peace treaties , all of which Iranians recollect as episodes of indelible national humiliation. Many understand the Russian Empire as having been an opportunistic neighbor. Today, Iranians also begrudge Russia’s endorsement of punitive UN Security Council resolutions between 2006 and 2010, which opened the floodgates to an avalanche of economic sanctions on the country. The Security Council members’ consensus to treat Iran’s nuclear program under Chapter VII of the United Nations Charter, which addresses threats to global peace and acts of aggression, communicated the urgency of countering Iran to all member states. Russia didn’t use its veto power then to shield a putatively strategic ally, and what was marketed as a special relationship remained Iran’s unrequited love. Still, at the height of the Islamic Republic’s tensions with the United States and Europe, the ruling elite in Tehran insisted that the Kremlin was a robust security anchor. When the war broke out in Ukraine, Iranians found a new reason to be resentful of Putin’s sprawling empire. Having endured eight years of occupation by the former Iraqi dictator Saddam Hussein, they recognized what it meant to be caught in the crosshairs of a foreign adversary’s wrath and bear witness to the unchecked loss of life and decimation of one’s country’s infrastructure. The Islamic Republic’s position from the onset was to soft-pedal the war on Ukraine and implant Moscow’s framing of the invasion as a “special military operation” in the local media coverage. Yet, Russia’s expansionist project struck a chord only with an enclave of hidebound government patrons. Independent journalists have been among the most outspoken groups in Iran, facing government backlash for criticizing Russia and covering the unfolding crisis without abandoning their ethical standards. The nation’s most hardline newspaper, Kayhan , run by a representative of the supreme leader Ayatollah Ali Khamenei, routinely pillories the Iranian supporters of Ukraine, including newspapers denouncing Russia, as traitors besotted by the West. But solidarity with Ukraine has also been expressed by the nation’s religious-minded communities. Ahead of the fasting month of Ramadan in 2022, a religious congregation in Tehran caught the worshippers and observers off-guard by erecting flags of Yemen and Ukraine together as part of its setting design, predicated on the belief that Shia Islam is supposed to aid and honor the oppressed. Around the same time, in an interview with Asia Newspaper , Ukraine’s then-ambassador in Iran Sergey Burdylyak, said his observations in Tehran reflected strong support for Ukraine as it defended itself against Russia. He said he was heartened to see people waving the Ukrainian flag everywhere. On February 26, 2022, a group of Tehran residents gathered in front of the Ukrainian embassy, carrying the flag of Ukraine and vigil candles. Security forces didn’t take long to disperse them forcibly, but the protesters still chanted “Death to Putin,” calling the Russian embassy a “den of espionage.” Against this backdrop, as President Zelenskyy ups the war of words with Tehran, Iranians are also asking questions they previously hadn’t reckoned with: Has Ukraine ever called for the removal of the economic sanctions inflicting despair on Iranians’ lives? Has Zelenskyy voiced support for the pro-democracy, women’s rights movement in Iran that has inspired millions worldwide? Has he called for the release of Iranians who, like him, have been fighting for the liberty of their people, such as the 2023 Nobel Peace Prize recipient Narges Mohammadi, who is now behind bars in the Iranian capital? Tehran’s continued provision of armaments to Russia is not only objectionable — it marks the hypocrisy of a government that had for years boasted of its opposition to militarism and oppression. Iranian drones and ballistic missiles have fueled a war machine that has subdued the Ukrainian people and upended their lives. The magnitude of damage wrought by these weapons has been documented in detail. But with the understanding that Iranians aren’t a monolith and that the government’s unilateral outreach to Putin is an unpopular position domestically, couldn’t Ukraine’s president chart a different path that would bolster his defense against Russia while giving him the chance to play the long game on ties with Iran? It wouldn’t have been costly for Zelenskyy to talk to Iran’s new President Masoud Pezeshkian in the same vein he engaged the leaders of Turkey, Saudi Arabia and the UAE. Since the day he came to power, Pezeshkian made it clear that he was in favor of peace, that he wished to restore normalcy in Iran’s foreign relations, and that he wanted to turn the tide domestically and contain religious extremism. In Pezeshkian, Zelenskyy could find a partner for understanding. The Ukrainian president’s anti-war platform could also benefit from keeping the Iranian people onboard. They seem to be losing interest as he has.

Silver Voices is calling on all MPs not to duck this rare opportunity to agree legislation to enshrine the right of a terminally ill patient to choose the exact place and time of their death. Who wants to pass away comatose on a hospital bed, undignified with multiple tubes everywhere, and unable to say goodbye to close family and friends? Who wants to spend their last few weeks in pain, gradually losing control of their functions and increasingly unable to communicate? Who wants loving partners to be criminalised because they are trying to carry out their loved one’s last wishes? A ‘good death’ is what we all hope for, and is so important for family memories too. Older people are the most likely to face these dilemmas and yet there has been no organisation bold enough to find out what senior citizens think about this topic. We have tested our membership in a big anonymous poll about whether they support the precise Bill being voted on and a significant majority has voiced its support. But we do recognise that a sizeable minority of our members has worries about the Bill, particularly whether the safeguards will prevent a slippery slope from a choice for assisted dying to an expected duty on older people to do so. Also, there is great concern, even amongst the Bill’s supporters, that the poor state of palliative and social care in the UK will force people to choose the assisted dying option when they shouldn’t have to do so. Questions have also been raised on practicalities such as whether insurance policies could be invalidated. If, as I hope, the Bill passes its Second Reading this week, it will be incumbent on the Government to ensure there is as much time as possible to debate the complications and worries of opponents and to agree sensible amendments to strengthen safeguards. Squeezing scrutiny time on such consequential legislation would indicate that the Government is not serious about supporting the principle of assisted dying. If the Bill does not get through its Second Reading or is scuppered by a lack of parliamentary time, we may have to wait many more years for the issue to be considered again.NEW YORK — A familiar face will help the Jets with their general manager and coaching search. Gang Green has hired The 33rd Team, founded by former Jets General manager and senior vice president of football operations Mike Tannenbaum, to help them find candidates for their general manager and coaching vacancies, according to sources. Former Vikings general manager Rick Spielman will also help Tannenbaum identify candidates for the roles. The 33rd Team will also provide data analysis and experience to assist the Jets in seeking new leadership. The Jets fired both general manager Joe Douglas and coach Robert Saleh during this season. Owner Woody Johnson fired Saleh on Oct. 8 and Douglas on Nov. 19. Johnson will supervise both the general manager and coaching searches but will receive help from The 33rd Team and others within the Jets organization, who will also be involved in the search. Spielman was an advisor to the Commanders in 2024 in their search for the team’s new head coach and general manager. Washington ultimately hired Adam Peters as its general manager and Dan Quinn as coach. The Commanders currently have a 7-5 record and have been one of the surprise teams in the league this season. Tannebaum started with the Jets organization in 1997 as a director of player contracts. He became the team’s director of pro player development in 2000 and later the general manager and director of pro personnel from 2006-12. Tannebaum was also the last general manager to have significant success for the Jets. He was the architect of the Jets teams that went to back-to-back AFC Championships in 2009 and 2010. Since then, the Jets have missed the playoffs for 13 consecutive seasons, the longest playoff drought in North American sports. Under Tannebaum, the Jets drafted cornerstone players such as Pro Football Hall of Famer Darrelle Revis, D’Brickashaw Ferguson, and Nick Mangold. He also hired former Jets coaches Eric Mangini and Rex Ryan during his tenure as general manager. In 2012, Tannebaum was fired following the Jets 6-10 record. In 2015, Tannebaum became the Dolphins executive vice president of football operations until owner Stephen Ross fired him in 2018. The Jets previous three general managers following Tannenbaum’s departure, John Idzik Jr., Mike Maccagnan, and Douglas, all failed to make the playoffs during their tenures. Maccagnan is the only Jets general manager to record a winning record (2015) since 2010. Gang Green is officially in rebuild mode after Johnson fired Saleh and Douglas. The team entered the 2024 season with not just playoff expectations but Super Bowl aspirations. But with a 3-8 record with six games, the Jets are poised to miss the playoffs for the 14th straight season. After beginning the season 2-3, Johnson fired Saleh and made defensive coordinator Jeff Ulbrich interim coach. Johnson felt like the Jets were underachieving after calling the roster the best during his 25 seasons as owner. Since Johnson fired Saleh, the Jets are 1-5 and are tied for last place in the AFC East with the Patriots. During the bye last week, Johnson fired Douglas so the team could begin their general manager and coaching search. Douglas was in the final year of his contract, which he signed in 2019. The Jets are one of two coaching vacancies currently open. The Saints fired coach Dennis Allen on Nov. 4 following a 2-7 start. The Jets can currently interview any potential candidate who does not work for an NFL team. If they want to interview candidates currently working for any of the 32 teams, the Jets will have to wait until Jan. 5, the conclusion of the regular season. ©2024 New York Daily News. Visit nydailynews.com . Distributed by Tribune Content Agency, LLC.

Push comes as Syria’s new de facto leader Ahmed al-Sharaa met Bahraini, Libyan delegations in Damascus. Syria’s new administration is carrying out a security crackdown against what it has described as “remnants” of former President Bashar al-Assad’s rule, with operations under way in several parts of the country. The official Syrian news agency SANA reported on Saturday that authorities were conducting “a large-scale sweep operation” near the city of Latakia on Syria’s northwestern coast. The push — in an area where al-Assad enjoyed support from the Alawite community — came in response to “reports about [the] presence of elements linked to remnants of Assad’s militias”, SANA said in a post shared on social media. Reporting from the capital Damascus, Al Jazeera’s Hashem Ahelbarra explained that the new administration said it is not targeting the Alawite community, from which al-Assad hailed. Instead, the authorities said the security operation has focused on soldiers and Syrian army officials associated with al-Assad and his brother, Maher al-Assad, a powerful former military commander. “They say that [they’ve] issued an ultimatum to those people to hand over weapons to the new administration,” Ahelbarra reported, adding that operations also were being carried out in Homs, Aleppo and on the outskirts of Damascus. The push comes days after 14 police officers were killed in what the authorities said was an “ambush” by forces loyal to al-Assad in the Tartous governorate, another area on Syria’s western coast. Interior Minister Mohammed Abdul Rahman had promised on Thursday to crack down on “anyone who dares to undermine Syria’s security or endanger the lives of its citizens”. Syrian opposition groups led by Hayat Tahrir al-Sham (HTS) took control of the country earlier this month after a rapid offensive that ousted al-Assad after more than two decades in power. A political transition is under way, with Syria’s new de facto leader Ahmed al-Sharaa – who headed HTS and previously had ties to al-Qaeda – holding talks with a number of Arab and Western diplomats in recent days. Several countries have urged al-Sharaa to ensure that religious and ethnic minorities will be protected amid some recent tensions and fears that any unrest could negatively affect Syria and the wider region. “What happens next in Syria will not only have an impact on the Syrians themselves, but it could spread beyond the country,” said Al Jazeera’s Ahelbarra. “This is why people are concerned about what happens next.” Al-Sharaa, also known as Abu Mohammed al-Julani, met with a Bahraini delegation in Damascus on Saturday, as well as with a senior official from Libya’s United Nations-recognised government. “We expressed our full support for the Syrian authorities in the success of the important transitional phase,” Libyan Minister of State for Communication and Political Affairs Walid Ellafi told reporters after the meeting. “We emphasised the importance of coordination and cooperation ... particularly on security and military issues,” Ellafi said, while the pair also discussed cooperation “related to energy and trade” and “illegal immigration”. Meanwhile, Lebanese officials and a war monitor said Lebanon expelled approximately 70 Syrian officers and soldiers on Saturday, returning them to Syria after they crossed into the country illegally via informal routes. Many senior Syrian officials and people close to the al-Assad family fled the country to neighbouring Lebanon after al-Assad was toppled on December 8. The Syrian Observatory for Human Rights (SOHR), a London-based monitor, said Syrian military personnel of various ranks had been sent back via Lebanon’s northern Arida crossing. SOHR and a Lebanese security official told the Reuters news agency that the returnees were detained by the new Syrian authorities after crossing the border.

ESTERO, Fla. (AP) — Al Green scored 19 points and Sean Newman Jr. added seven in the overtime as Louisiana Tech knocked off Southern Illinois 85-79 in a first-round contest at the Gulf Coast Showcase on Monday night. Green had three steals for the Bulldogs (5-0). Kaden Cooper scored 18 points and added 12 rebounds and four steals. Amaree Abram went 8 of 13 from the field to finish with 18 points, while adding six steals. Kennard Davis led the way for the Salukis (2-4) with 16 points, 10 rebounds and three steals. Southern Illinois also got 15 points and eight rebounds from Jarrett Hensley. Ali Abdou Dibba also had 12 points and two steals. Cooper scored 12 points in the first half and Louisiana Tech went into the break trailing 31-27. Abram's 16-point second half helped Louisiana Tech close out the six-point victory. NEXT UP These two teams both play Tuesday in the six-team, round-robin tournament. Louisiana Tech squares off against Richmond and Southern Illinois faces Eastern Kentucky. The Associated Press created this story using technology provided by Data Skrive and data from Sportradar .

Panthers TE Ja'Tavion Sanders carted off field for neck injury

Reynolds puts up 22 for St. Joseph's in 76-58 victory over Delaware StateDonald Hand Jr. racked up a career-high 29 points and 10 rebounds to help Boston College stave off visiting Fairleigh Dickinson 78-70 on Saturday in Chestnut Hill, Mass. Chad Venning added 18 points on 8-for-10 shooting and Dion Brown contributed eight points, eight rebounds and four assists as the Eagles (8-5) wrapped up their nonconference slate with just their second win in six games. Ahmed Barba-Bey, a grad transfer from Division II, exploded for a season-high 31 points to power FDU (4-11). Barba-Bey buried 8 of 9 attempts from the 3-point arc. Terrence Brown added 15 of his 20 points in the second half, as the Knights made it close before falling to 0-10 on the road this season. Bismark Nsiah scored 10 points. Boston College led 70-59 with 3:39 to play when Barba-Bey was fouled attempting a corner 3. He made all three of his foul shots, and after a stop Brown got to the bucket to cut FDU's deficit to six. It was 72-67 when Venning made a clutch turnaround jumper from the high post with 51 seconds left. Boston College let Barba-Bey get loose for his eighth 3-pointer, pulling FDU within four, its closest margin of the half. But Hand drove to the basket and scored with 29 seconds on the clock, and FDU was out of time. The Knights trailed by as many as 12 in the first half, but Barba-Bey kept them in the game. He made a fastbreak layup off Brown's steal and added a 3-pointer on the next possession, turning what was a 10-point deficit to a manageable 29-24 game. Boston College led 38-28 at halftime, with Hand scoring 15 for the hosts and Barba-Bey pouring in 16 for the Knights, including 4-of-5 shooting from deep. FDU pulled within nine points three times in the early stages of the second half, the third coming when Nsiah knocked down back-to-back 3-pointers to make it 56-47 with about 10 minutes to go. --Field Level Media

By MICHELLE L. PRICE WEST PALM BEACH, Fla. (AP) — President-elect Donald Trump appears to be siding with Elon Musk and his other backers in the tech industry as a dispute over immigration visas has divided his supporters. Trump, in an interview with the New York Post on Saturday, praised the use of visas to bring skilled foreign workers to the U.S. The topic has become a flashpoint within his conservative base. “I’ve always liked the visas, I have always been in favor of the visas. That’s why we have them,” Trump said. In fact, Trump has in the past criticized the H-1B visas, calling them “very bad” and “unfair” for U.S. workers. During his first term as president, he unveiled a “Hire American” policy that directed changes to the program to try to ensure the visas were awarded to the highest-paid or most-skilled applicants. Despite his criticism of them and attempts to curb their use, he has also used the visas at his businesses in the past, something he acknowledged in his interview Saturday. “I have many H-1B visas on my properties. I’ve been a believer in H-1B. I have used it many times. It’s a great program,” Trump told the newspaper. He did not appear to address questions about whether he would pursue any changes to the number or use of the visas once he takes office Jan. 20. Trump’s hardline immigration policies, focused mostly on immigrants who are in the country illegally, were a cornerstone of his presidential campaign and a priority issue for his supporters. But in recent days, his coalition has split in a public debate largely taking place online about the tech industry’s hiring of foreign workers. Hard-right members of Trump’s movement have accused Musk and others in Trump’s new flank of tech-world supporters of pushing policies at odds with Trump’s “America First” vision. Software engineers and others in the tech industry have used H-1B visas for skilled foreign workers and say they are a critical tool for hard-to-fill positions. But critics have said they undercut U.S. citizens who could take those jobs. Some on the right have called for the program to be eliminated.

Demi Moore revealed how actor Bruce Willis almost two years after he was revealed his dementia diagnosis . Ex-wife Moore answered questions on CNN about his ongoing health battle, saying that he “in a very stable place at the moment.” “I’ve shared this before, but I really mean this so sincerely,” Moore said. “It’s so important for anybody who’s dealing with this, to really meet them where they’re at, and from that place, there is such loving and joy.” In 2022, Willis' family announced his aphasia diagnosis, a language disorder that makes it hard for those to communicate or understand others. In 2023, they learned the aphasia was a result of frontotemporal dementia. “I’ve known that something was wrong for a long time. It started out with a kind of vague unresponsiveness, which the family chalked up to Hollywood hearing loss,” his daughter Tallulah Willis wrote in Vogue in 2023. “I find that I’m trying to document, to build a record for the day when he isn’t there to remind me of him and of us.” His second wife, Emma Heming Willis, currently is the actor’s caretaker. Moore emphasized that Willis' condition is “very difficult,” and said that she wouldn’t wish it on anyone. “There is great loss,” Moore said. “but there is also great beauty.” Soap opera star Thom Christopher died on Dec. 5 at the age of 84. Christopher starred as villain Carlo Hessler on the long-running soap One Life to Live . Former co-star Anthony Crivello announced his death in a Facebook with a heartfelt message. “He was always a gentleman, always supportive, and he and his wife Judith who proceeded him in death, where always gracious to me and welcoming,” Crivello, who played Christopher’s son, wrote. Christopher’s wife Judith died in 2019. “May Thom fly on Wings of Angels to be beside his beloved Judith, and may they enjoy each other’s company once again, beside the ‘Pearly Gates’ of heaven.” Christopher appeared on the series from 1991 to 2008. One Life to Live ran from 1956 until 2013. In 1992, he won a daytime Emmy for best supporting actor for his work on the show. The name TASER is already synonymous with public safety, with professionals everywhere relying on them for unparalleled protection in all kinds of situations. If you want to get the same sense of security and peace of mind, the TASER Pulse 2 is here to meet your needs. The TASER Pulse 2 is the ultimate compact solution for less-lethal self-defense. Like all TASER devices, the Pulse 2 is designed to empower you to take control of your safety with confidence and clarity while lessening the risk of accidentally hurting yourself (or worse). The TASER Pulse 2 has a traditional compact gun design, making it concealable, easy to carry, and perfect for incorporating into your everyday life , so you can feel fully prepared for any situation that may arise. As the saying goes: if you stay ready, you don’t have to get ready. The TASER Pulse 2 also makes the perfect gift to share with a loved one during this holiday season. After all, you can’t put a price on feeling protected! Whether you’re buying for yourself or someone you care about, now is the perfect time to invest in security by grabbing this reliable tool. If you buy something from this post, we may earn a small commission. Randy Moss, former wide receiver, Hall of Famer and current ESPN pundit for “Sunday NFL Countdown,” is stepping back from the show due to heath issues, according to the network. The hiatus, announced on Friday, comes after an Instagram post by Moss on Sunday asking for prayers. In the video, he said he has been battling “something internal,” and that he has a “great team of doctors.” The star then referred to viewers mentioning his seemingly yellow eyes last week, and put on a pair of sunglasses. “Your boy is going to get through it,” Moss said. “So if you see me with my... glasses on, y’all know what I’m battling,” ESPN said Moss had the network’s “full support’ and that they “look forward to welcoming him back when he is ready.” In the Instagram video, Moss, 47, told men to get their check-ups and bloodwork done. “I just ask for all the prayer warriors to put their blessing hands on me and my family through these hard times,” Moss said. A post shared by Randygmoss (@randygmoss) Britney Spears didn’t move to Mexico— despite the video of Spears saying she did, a source told The Hollywood Reporter . The singer originally told fans that she moved to Mexico to escape the “incredibly cruel” paparazzi. “It really kind of hurts my feelings that the paparazzi make my face look like I’m wearing like a white Jason mask, and it doesn’t even look like me,” Spears said on Tuesday. “They’ve always been incredibly cruel to me, the paparazzi and pictures and the way they’ve illustrated me to be in some of it. I know I’m not perfect at all, by any means, but some of it is extremely mean and cruel, and that’s why I’ve moved to Mexico.” The clip was part of a longer video marking Spears’ 43rd birthday on Monday, which was also the day her divorce with Sam Asghari was finalized, according to TMZ . Scouted selects products independently. If you purchase something from our posts, we may earn a small commission. If you’re looking to revamp your at-home fitness lineup ahead of 2025 and don’t have hours to commit to exercising each day, allow us to introduce you to the CAROL Bike . 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The company argued that it violated the First Amendment. “The First Amendment exists to protect free speech in the United States,” said the court’s opinion, written by Judge Douglas Ginsburg. “Here the Government acted solely to protect that freedom from a foreign adversary nation and to limit that adversary’s ability to gather data on people in the United States.” TikTok and ByteDance are expected to appeal the decision to the Supreme Court, though it’s unclear if the Court would hear the case. The ban was signed into law by Joe Biden in April, capping off a years-long fight against the popular app, which lawmakers view as a threat to national security. Two hikers reportedly stumbled upon a woman tied to a tree and crying in Monterey County, California, on Wednesday. According to SF Gate , she was walking a trail in Pebble Beach around 7:30 that morning when she noticed a “suspicious male” behind her, holding a gun. The man did not take anything from her or assault her or injure her, just left her tied up for two hours before the passersby found her. With the help of another hiker, he untied the woman and called the police. The Monterey County Sheriff’s Office subsequently launched a search for the suspect, described as being in his 30s with a neck tattoo involving the letter Z. SFGate reports that while authorities haven’t identified anyone matching that description yet, they say there is “no active threat to the community.” Confusing celebrity update: Paris Jackson, daughter of late musician Michael Jackson , is engaged to Justin Long. Not the Justin Long I think you’re thinking of (he’s married to Kate Bosworth) but another Justin Long; the Justin Long who Jackson has been dating for about two years. He works as a music producer, sound engineer, and mixer, according to The Daily Mail , and first appeared on Jackson’s Instagram in Nov. 2022. The next time he showed up on her grid was Friday, in a carousel she posted to celebrate Long’s birthday, which also included photos of the proposal. “Happy birthday, my sweet blue,” she captioned the post, using her nickname for her fiancé. “Doing life with you these last years has been an indescribable whirlwind and I couldn’t dream of anyone more perfect for me to do it all with.” As for when the pair became engaged, Jackson was photographed wearing a big diamond ring during Paris Fashion Week this past September. Consider this the hard launch? The jury in Daniel Penny’s manslaughter case signaled Friday that they’re struggling to reach a verdict on the case. They must decide if Penny “recklessly” caused the death of Jordan Neely by putting him in a six-minute chokehold on the subway in May 2023. Penny’s attorneys argued that the former Marine was justified in putting Neely in a chokehold because witnesses say he told passengers, “Somebody’s going to die today,” and that he was ready to go to jail. Prosecutors argue that no witnesses testified that Neely brandished a weapon or touched anybody, and that Penny kept Neely in the chokehold long after other passengers left the train. The jury has been deliberating since Tuesday. The jury could also convict him of the lesser charge of criminally negligent homicide. If the jury can’t reach a verdict then Manhattan Supreme Court Justice Maxwell Wiley would issue an “Allen” charge, which urges them to reach a unanimous verdict. Penny faces up to 15 years in prison if convicted on the manslaughter charge, or up to four years if convicted of a lesser count. Scouted selects products independently. If you purchase something from our posts, we may earn a small commission. 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Say goodbye to messes and hello to your new printer . Best of all? For a limited time, score three months of Instant Ink with HP+. Donald Trump on Friday fired off an unequivocal message of support for his defense secretary pick Pete Hegseth in the wake of several damaging reports about the Fox News star’s alleged behavior. “Pete Hegseth is doing very well. His support is strong and deep, much more so than the Fake News would have you believe,” the president-elect wrote on Truth Social. “He was a great student—Princeton/Harvard educated—with a Military state of mind. He will be a fantastic, high energy, Secretary of Defense Defense, one who leads with charisma and skill. Pete is a WINNER, and there is nothing that can be done to change that!!!” Trump’s post came the morning after Hegseth spent the day meeting with senators whose votes he’ll need to be confirmed as the next Pentagon chief. Speaking to reporters Thursday, Hegseth insisted he’d had a “ great week ”—despite multiple bombshell reports emerging in recent days about his alleged drunken antics, which he denies, along with rumors that Trump is considering replacing him with Florida Gov. Ron DeSantis as his nominee for defense secretary. “As long as Donald Trump wants me in this fight, I’m going to be standing right here in this fight,” Hegseth said. A top Romanian court alleged Friday that Russia conducted an elaborate TikTok psy op to get a pro-Putin political newcomer elected president. The European Union member state’s Constitutional Court made the unprecedented decision to annul the results after the first round of its election votes, with Sunday’s second round of voting canceled, too. A raft of now-released intelligence reports allege that front-runner Calin Georgescu soared into the lead backed by 25,000 TikTok accounts based in Moscow. The Euro skeptic and anti-NATO Georgescu, who has professed his admiration of Romania’s fascist past, was a relative nobody before the election and was polling at around 5 percent. The U.S. State Department said earlier this week that it was concerned by the Romanian Supreme Council of National Defense’s “report of Russian involvement in malign cyber activity designed to influence the integrity of the Romanian electoral process.”Warren Buffett gives away another $1.1B and plans for distributing his $147B fortune after his death

NoneMusk's millions for Trump make him biggest US political donorAP Sports SummaryBrief at 5:21 p.m. EST‘MITRA’ should be guiding force in boosting priority sectors Fadnavis