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Gene editing technology is being widely deployed to generate precise data about disease-causing gene mutations and networks, helping to identify optimal therapeutic targets. These approaches are fueling efforts to develop cell and gene therapies for a growing number of genetic disorders among an estimated 6,000 Mendelian diseases, most of which still lack cures. In this webinar, our expert panelists will discuss recent insights into the relationship between human genetic variation and disease from functional genomic studies. They will share their preferred strategies for improving payload development and delivery in functional genomics studies using gene editing. Key takeaways include: · An understanding of the complexities of therapeutic development including cell and gene engineering and manufacturing challenges. · An introduction to Revvity’s Dharmacon product suite—solutions for targeted editing in almost any cell type including CRISPR knockout, knock-in, and interference.

Moreover, the pressure to conform to unrealistic beauty standards, perpetuated by social media, has created a culture where cosmetic enhancements are seen as a quick fix to self-esteem issues and insecurities. The pursuit of physical perfection at any cost can have devastating consequences, as evidenced by the untimely demise of the female internet celebrity.Liu Damaeli, whose real name is Liu Xin, was a well-known figure in the world of social media, with a large following on various platforms. Her glamorous lifestyle, fashion sense, and beauty tips had captivated audiences and earned her a significant following. However, on that fateful day, what was supposed to be a routine cosmetic procedure turned into a tragedy.You block, I’ll dodge: Does internet censorship really work?

India captain's wife posts bizarre social media message claiming her husband's 'booty' is better than his bowlingGlobal stocks end mostly up with DAX crossing 20,000 for 1st time

In the heart-pounding world of weightlifting, where strength, technique, and mental fortitude converge, a fierce showdown unfolded recently as the North Korean women's weightlifting team seized the upper hand in a thrilling competition against their South Korean counterparts. With the world watching, the rivalry between the two powerhouses of the sport reached new heights, captivating audiences and showcasing the pinnacle of athletic prowess.

Wearable robot 'X-ble Shoulder' to boost industrial efficiency and reduce musculoskeletal injuries Designed to assist overhead work by enhancing upper arm muscle strength, expected to find use in various industries The strong yet lightweight X-ble Shoulder enhances worker comfort by reducing shoulder load by 60% and muscle activity by 30% Hyundai Motor and Kia's Robotics LAB announced commercialization plan for X-ble Shoulder, expected to begin deliveries in first half of 2025 SEOUL, South Korea , Nov. 27, 2024 /PRNewswire/ -- Hyundai Motor Company and Kia Corporation have unveiled a reliable companion for industrial work, the wearable robot 'X-ble Shoulder.' This device, just by being worn, can increase workers' efficiency and reduce musculoskeletal injuries. Two videos released on Hyundai Motor Group's YouTube channel show the X-ble Shoulder in action, including product features and the development story . Hyundai Motor and Kia unveiled the X-ble Shoulder at Wearable Robot Tech Day held at the Hyundai Motorstudio Goyang near Seoul . The X-ble brand — a combination of 'X,' symbolizing infinite potential, and 'able,' indicating that anything can be realized — heralds a new era in wearable technology. The X-ble Shoulder, the first product in the X-ble line, is an industrial wearable robot developed by Hyundai Motor and Kia's Robotics LAB. When used in 'overhead work' where the arm is raised, it can assist the user's upper arm muscle strength and reduce the burden on the upper extremity musculoskeletal system. The X-ble Shoulder will find use in various industries, including construction, shipbuilding, aviation and agriculture, not just automobiles. Following its domestic launch, the companies plan to gradually expand sales to overseas markets. In addition to the X-ble Shoulder, Hyundai Motor and Kia plan to develop an industrial wearable robot 'X-ble Waist' to assist the waist when lifting heavy loads, and a medical wearable robot 'X-ble MEX' for the rehabilitation of the walking impaired. "The X-ble Shoulder is a wearable robot that leverages the technical capabilities of the Robotics LAB and implements feedback from actual users," said Dong Jin Hyun , Vice President and Head of Robotics LAB at Hyundai Motor and Kia. "Going forward, we aim to expand the availability of wearable robots, creating products that work naturally with users to enhance their daily lives. By pushing technological boundaries, we will make these beneficial products accessible to more people." View original content to download multimedia: https://www.prnewswire.com/news-releases/hyundai-motor-and-kias-robotics-lab-announce-plans-to-launch-x-ble-shoulder-at-wearable-robot-tech-day-302317253.html SOURCE Hyundai Motor Company; Kia CorporationMicrosoft announces quarterly dividend

The decision sent shockwaves through the football world, with fans, pundits, and rival clubs all weighing in on the implications of the ruling. Manchester City supporters rejoiced at the news, seeing it as a validation of their club's integrity and a chance to compete on equal footing with Europe's elite once again.

Celebrate the Season with Snoopy Decorations at Lowe'sAs the investigation unfolds and the Special Committee delves deeper into the potential wrongdoing of the Prime Minister and 11 others, South Korea finds itself at a crossroads. The outcome of the probe could have far-reaching implications for the nation's political landscape, shaping the course of its future and the trust of its citizens in the government.

In the realm of video gaming, Non-Player Character (NPC) companions have long been a staple in providing support, guidance, and sometimes comic relief to players on their virtual adventures. However, one persistent issue that has plagued many players is the incessant and often irrelevant chatter that these NPC companions engage in, making the gaming experience less immersive and more irritating. But fear not, for a new dawn is upon us with the groundbreaking introduction of the "Oath of Silence" in NPC companion programming.In Pakistan, women’s rights, harassment and other related issues take centre stage mostly in March, when controversy around the Aurat March splashes across the media. The fact is, almost all working women face harassment at work, during commutes, and elsewhere. This must become a constant discussion to bring about real change. The Home-Based Women Workers Federation (HBWWF) has revealed alarming figures that 85 per cent of women workers in Pakistan experience workplace harassment. The number touches 90 per cent for domestic help. The reality is that our societal norms have entrenched this menace. Values can be changed through awareness and laws. The Workplace Harassment Act of 2010 is a good legislative piece, but without enforcement, it is toothless. Harassment cases, reported to relevant forums, often face judicial delays and social apathy. Harassment is not confined to workplaces. Women face constant harassment in the digital sphere; almost all women face online harassment but only 40 per cent of them report them. Domestic violence against women remains rampant. Physical and sexual abuse remains widespread. These challenges are compounded for women from religious minorities. They are denied inheritance rights despite legal protections. The statistics paint a bleak picture. Women make up 49.4 per cent of the working-age population. Sadly, they account for only 23.5 percent of the labour force, as per the Pakistan Labour Force Survey. Pakistan ranked 143 out of 146 on the Global Gender Gap Index of 2023. Women in Pakistan do not only battle misogynistic attitudes but also fight for democracy, children’s rights, equality, social and judicial justice and better social conditions. Present-day stories of activists like Sammi Baloch and Sorath Lohar show that women have always stood at the forefront of resistance. The demands of Baloch women for the return of their loved ones reflect the heartbreaking struggles of marginalised groups. Lip service, grim data figures and heart-breaking stories may not bring about a visible change. We need to go beyond lip service. What can change the scenario are economic opportunities for women, equal pay and a harassment-free workplace. These are not privileges but rights. Inclusive measures are essential for true political representation. Moreover, the plight of incarcerated women cannot be ignored. Poor prison conditions, lack of legal support, and healthcare access must be urgently addressed. The time for action is long overdue. *International News: UNICEF report shows children recruited by gangs in Haiti soars by 70%Los Angeles Lakers Reportedly Interested In Veteran Forward

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In response to the arrest of President Yun Seok-yuet, the government has launched a thorough investigation into the allegations of corruption and abuse of power. The Internal Affairs Department has been tasked with leading the inquiry, with full support from the parliament and the judiciary. The investigation is expected to be swift and transparent, with the goal of uncovering the truth and holding all those responsible accountable for their actions.